A review and database of snake venom proteomes

T Tasoulis, GK Isbister - Toxins, 2017 - mdpi.com
Advances in the last decade combining transcriptomics with established proteomics
methods have made possible rapid identification and quantification of protein families in …

Multifunctional toxins in snake venoms and therapeutic implications: from pain to hemorrhage and necrosis

CR Ferraz, A Arrahman, C Xie, NR Casewell… - Frontiers in ecology …, 2019 - frontiersin.org
Animal venoms have evolved over millions of years for prey capture and defense from
predators and rivals. Snake venoms, in particular, have evolved a wide diversity of peptides …

Venomics: integrative venom proteomics and beyond

JJ Calvete - Biochemical Journal, 2017 - portlandpress.com
Venoms are integrated phenotypes that evolved independently in, and are used for
predatory and defensive purposes by, a wide phylogenetic range of organisms. The same …

Snakebite envenoming diagnosis and diagnostics

C Knudsen, JA Jürgensen, S Føns, AM Haack… - Frontiers in …, 2021 - frontiersin.org
Snakebite envenoming is predominantly an occupational disease of the rural tropics,
causing death or permanent disability to hundreds of thousands of victims annually. The …

The urgent need to develop novel strategies for the diagnosis and treatment of snakebites

HF Williams, HJ Layfield, T Vallance, K Patel… - Toxins, 2019 - mdpi.com
Snakebite envenoming (SBE) is a priority neglected tropical disease, which kills in excess of
100,000 people per year. Additionally, many millions of survivors also suffer through …

Snake venomics: from the inventory of toxins to biology

JJ Calvete - Toxicon, 2013 - Elsevier
A deep understanding of the composition of venoms and of the principles governing the
evolution of venomous systems is of applied importance for exploring the enormous …

Integrated “omics” profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, Crotalus simus …

J Durban, A Pérez, L Sanz, A Gómez, F Bonilla… - BMC genomics, 2013 - Springer
Background Understanding the processes that drive the evolution of snake venom is a topic
of great research interest in molecular and evolutionary toxinology. Recent studies suggest …

Combined venomics, venom gland transcriptomics, bioactivities, and antivenomics of two Bothrops jararaca populations from geographic isolated regions within the …

L Gonçalves-Machado, D Pla, L Sanz, RJB Jorge… - Journal of …, 2016 - Elsevier
Bothrops jararaca is a slender and semi-arboreal medically relevant pit viper species
endemic to tropical and subtropical forests in southern Brazil, Paraguay, and northern …

New approaches & technologies of venomics to meet the challenge of human envenoming by snakebites in India

DA Warrell, JM Gutiérrez, JJ Calvete… - Indian Journal of …, 2013 - journals.lww.com
The direct estimate of 46,000 snakebite deaths in India in 2005 (1 for every 2 HIV/AIDS
deaths), based on verbal autopsies, renders unrealistic the total of only 47,000 snakebite …

Jellyfish venomics and venom gland transcriptomics analysis of Stomolophus meleagris to reveal the toxins associated with sting

R Li, H Yu, W Xue, Y Yue, S Liu, R Xing, P Li - Journal of Proteomics, 2014 - Elsevier
Jellyfish Stomolophus meleagris is a very dangerous animal because of its strong toxicity.
However, the composition of the venom is still unclear. Both proteomics and transcriptomics …