Amphetamine-related drugs, such as 3, 4-methylenedioxymethamphetamine (MDMA) and
methamphetamine (METH), are popular recreational psychostimulants. Several preclinical …

Schizophrenia is characterized by profound cognitive deficits that are not alleviated by
currently available medications. Many of these cognitive deficits involve dysfunction of the …

INTRODUCTION The drive to seek and experience reward is conserved across species and,
in mammals, involves interactions between subcortical dopaminergic systems and limbic …

Neuronal signals have emerged as pivotal regulators of group 2 innate lymphoid cells
(ILC2s) that regulate tissue homeostasis and allergic inflammation. The molecular pathways …

The prefrontal cortex is thought to modulate sensory signals in posterior cortices during top-
down attention,, but little is known about the underlying neural circuitry. Experimental and …

Rationale Dopamine (DA) receptors within the nucleus accumbens (NAc) are implicated in
the rewarding properties of stimuli. Aggressive behavior can be reinforcing but the …

The dopaminergic system can adapt to the different physiological or pathological situations
to which the kidneys are subjected throughout life, maintaining homeostasis of natriuresis …

Approach to reward is a fundamental adaptive behavior, disruption of which is a core
symptom of addiction and depression. Nucleus accumbens (NAc) dopamine is required for …

Methamphetamine is a synthetic drug consumed by millions of users despite its neurotoxic
effects in the brain, leading to loss of dopaminergic fibres and cell bodies. Moreover, clinical …

Cannabinoids have been shown to critically modulate cholinergic neurotransmission in the
hippocampus, yet opposing effects of cannabinoid receptor 1 (CB1R) agonists on …