Understanding biological mechanisms is fundamental for improving animal production and
health to meet the growing demand for high-quality protein. As an emerging biotechnology …

Mammalian female reproduction requires a functional ovary. Competence of the ovary is
determined by the quality of its basic unit–ovarian follicles. A normal follicle consists of an …

The pig is an important model for studying human diseases and is also a significant livestock
species, yet its testicular development remains underexplored. Here, we employ single-cell …

Throughout the individual's reproductive period of life the ovary undergoes continues
changes, including cyclic processes of cell death, tissue regeneration, proliferation, and …

Introduction Understanding the sex determination mechanisms in birds has great
significance for the biological sciences and production in the poultry industry. Sex …

The gonadal primordial germ cells (PGCs) possess a unique state of pluripotency and X
chromosome activity. However, extensive evidence indicates developmental variability in …

Single-cell multi-omics sequencing has greatly accelerated reproductive research in recent
years, and the data are continually growing. However, utilizing these data resources is …

Primordial germ cells (PGCs) are the precursors of germline that are specified at embryonic
stage. Recent studies reveal that humans employ different mechanisms for PGC …

Accurate specification of female and male germ cells during embryonic development is
critical for sexual reproduction. Primordial germ cells (PGCs) are the bipotential precursors …

The ovary plays a crucial role in the reproductive system of female mammals by producing
mature oocytes through folliculogenesis. Non-human model organisms are extensively …