Adenosine receptors and the central nervous system
AM Sebastiao, JA Ribeiro - Adenosine receptors in health and disease, 2009 - Springer
The adenosine receptors (ARs) in the nervous system act as a kind of “go-between” to
regulate the release of neurotransmitters (this includes all known neurotransmitters) and the …
regulate the release of neurotransmitters (this includes all known neurotransmitters) and the …
Purinergic signaling orchestrating neuron-glia communication
P Agostinho, D Madeira, L Dias, AP Simões… - Pharmacological …, 2020 - Elsevier
This review discusses the evidence supporting a role for ATP signaling (operated by P 2 X
and P 2 Y receptors) and adenosine signaling (mainly operated by A 1 and A 2A receptors) …
and P 2 Y receptors) and adenosine signaling (mainly operated by A 1 and A 2A receptors) …
MT1 and MT2 Melatonin Receptors: Ligands, Models, Oligomers, and Therapeutic Potential
Numerous physiological functions of the pineal gland hormone melatonin are mediated via
activation of two G-protein-coupled receptors, MT1 and MT2. The melatonergic drugs on the …
activation of two G-protein-coupled receptors, MT1 and MT2. The melatonergic drugs on the …
[HTML][HTML] Pathophysiology of astroglial purinergic signalling
H Franke, A Verkhratsky, G Burnstock, P Illes - Purinergic signalling, 2012 - Springer
Astrocytes are fundamental for central nervous system (CNS) physiology and are the fulcrum
of neurological diseases. Astroglial cells control development of the nervous system …
of neurological diseases. Astroglial cells control development of the nervous system …
Release of adenosine and ATP during ischemia and epilepsy
N Dale, BG Frenguelli - Current neuropharmacology, 2009 - ingentaconnect.com
Eighty years ago Drury & Szent-Gyorgyi described the actions of adenosine, AMP (adenylic
acid) and ATP (pyrophosphoric or diphosphoric ester of adenylic acid) on the mammalian …
acid) and ATP (pyrophosphoric or diphosphoric ester of adenylic acid) on the mammalian …
The role of extracellular adenosine in chemical neurotransmission in the hippocampus and Basal Ganglia: pharmacological and clinical aspects
B Sperlágh, E Sylvester Vizi - Current topics in medicinal …, 2011 - ingentaconnect.com
Now there is general agreement that the purine nucleoside adenosine is an important
neuromodulator in the central nervous system, playing a crucial role in neuronal excitability …
neuromodulator in the central nervous system, playing a crucial role in neuronal excitability …
Functional and anatomical identification of a vesicular transporter mediating neuronal ATP release
ATP is known to be coreleased with glutamate at certain central synapses. However, the
nature of its release is controversial. Here, we demonstrate that ATP release from cultured …
nature of its release is controversial. Here, we demonstrate that ATP release from cultured …
Tuning and fine-tuning of synapses with adenosine
AM Sebastião, JA Ribeiro - Current neuropharmacology, 2009 - ingentaconnect.com
The 'omnipresence'of adenosine in all nervous system cells (neurons and glia) together with
the intensive release of adenosine following insults, makes adenosine as a sort of …
the intensive release of adenosine following insults, makes adenosine as a sort of …
[HTML][HTML] Receptor-receptor interactions as a widespread phenomenon: novel targets for drug development?
The discovery of receptor-receptor interactions (RRI) has expanded our understanding of
the role that G protein-coupled receptors (GPCRs) play in intercellular communication. The …
the role that G protein-coupled receptors (GPCRs) play in intercellular communication. The …
Antagonism of purinergic signalling improves recovery from traumatic brain injury
AM Choo, WJ Miller, YC Chen, P Nibley, TP Patel… - Brain, 2013 - academic.oup.com
The recent public awareness of the incidence and possible long-term consequences of
traumatic brain injury only heightens the need to develop effective approaches for treating …
traumatic brain injury only heightens the need to develop effective approaches for treating …