Safety and efficacy of phage therapy in difficult-to-treat infections: a systematic review

S Uyttebroek, B Chen, J Onsea… - The Lancet Infectious …, 2022 - thelancet.com
According to the latest reports from WHO, the incidence of antibiotic-resistant bacterial
infections is increasing worldwide, resulting in increased morbidity and mortality and a rising …

Emerging strategies to combat ESKAPE pathogens in the era of antimicrobial resistance: a review

MS Mulani, EE Kamble, SN Kumkar… - Frontiers in …, 2019 - frontiersin.org
The acronym ESKAPE includes six nosocomial pathogens that exhibit multidrug resistance
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …

The safety and toxicity of phage therapy: a review of animal and clinical studies

D Liu, JD Van Belleghem, CR de Vries, E Burgener… - Viruses, 2021 - mdpi.com
Increasing rates of infection by antibiotic resistant bacteria have led to a resurgence of
interest in bacteriophage (phage) therapy. Several phage therapy studies in animals and …

Emergent crisis of antibiotic resistance: A silent pandemic threat to 21st century

F Akram, M Imtiaz, I ul Haq - Microbial pathogenesis, 2023 - Elsevier
Antibiotic resistance has become an indispensably alarming menace to the global
community. The primary factors are overuse and abuse of antibiotics, lack of novel …

[HTML][HTML] Advantages and limitations of bacteriophages for the treatment of bacterial infections

N Principi, E Silvestri, S Esposito - Frontiers in pharmacology, 2019 - frontiersin.org
Bacteriophages (BPs) are viruses that can infect and kill bacteria without any negative effect
on human or animal cells. For this reason, it is supposed that they can be used, alone or in …

The microbiology of diabetic foot infections: a meta-analysis

KE Macdonald, S Boeckh, HJ Stacey, JD Jones - BMC infectious diseases, 2021 - Springer
Background Diabetic foot ulcers are a common complication of poorly controlled diabetes
and often become infected, termed diabetic foot infection. There have been numerous …

Translating phage therapy into the clinic: Recent accomplishments but continuing challenges

A Petrovic Fabijan, J Iredell, K Danis-Wlodarczyk… - Plos …, 2023 - journals.plos.org
Phage therapy is a medical form of biological control of bacterial infections, one that uses
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …

[HTML][HTML] Formulation, stabilisation and encapsulation of bacteriophage for phage therapy

DJ Malik, IJ Sokolov, GK Vinner, F Mancuso… - Advances in colloid and …, 2017 - Elsevier
Against a backdrop of global antibiotic resistance and increasing awareness of the
importance of the human microbiota, there has been resurgent interest in the potential use of …

Bacteriophage therapy as an alternative treatment for human infections. A comprehensive review

A Kakasis, G Panitsa - International journal of antimicrobial agents, 2019 - Elsevier
Bacteriophages, or phages, are viruses that infect bacteria. They were discovered around a
century ago and have been used ever since for therapeutic purposes, particularly in former …

Phages for biofilm removal

C Ferriol-González, P Domingo-Calap - Antibiotics, 2020 - mdpi.com
Biofilms are clusters of bacteria that live in association with surfaces. Their main
characteristic is that the bacteria inside the biofilms are attached to other bacterial cells and …