The burden of critical limb ischemia: a review of recent literature

S Duff, MS Mafilios, P Bhounsule… - Vascular health and …, 2019 - Taylor & Francis
Peripheral arterial disease is a chronic vascular disease characterized by impaired
circulation to the lower extremities. Its most severe stage, known as critical limb ischemia …

The interrelationship between diabetes mellitus and peripheral arterial disease

K Stoberock, M Kaschwich, SS Nicolay, N Mahmoud… - Vasa, 2020 - econtent.hogrefe.com
This systematic review examined the interrelationship between concomitant diabetes
mellitus (DM) and peripheral arterial disease (PAD). The objective was to determine …

Applicability of transcutaneous oxygen tension measurement in the assessment of chronic limb-threatening ischemia

B Leenstra, J Wijnand, B Verhoeven, O Koning… - …, 2020 - journals.sagepub.com
Transcutaneous oxygen tension measurement (TcPO2) is widely applied for the evaluation
of chronic limb-threatening ischemia (CLTI). Nevertheless, studies that focused on the …

Chronic limb-threatening ischemia and the need for revascularization

R Berchiolli, G Bertagna, D Adami, F Canovaro… - Journal of clinical …, 2023 - mdpi.com
Background: Patients presenting with critical limb-threatening ischemia (CLTI) have been
increasing in number over the years. They represent a high-risk population, especially in …

Prostanoids for critical limb ischaemia

V Vietto, JVA Franco, V Saenz, D Cytryn… - Cochrane Database …, 2018 - cochranelibrary.com
Background Peripheral arterial occlusive disease (PAOD) is a common cause of morbidity
and mortality due to cardiovascular disease in the general population. Although numerous …

Critical limb ischemia: a practical up-to-date review

I Fabiani, E Calogero, NR Pugliese, R Di Stefano… - …, 2018 - journals.sagepub.com
Critical limb ischemia (CLI) is the most advanced form of peripheral artery disease. It is
associated with significant morbidity and mortality and high management costs. It carries a …

Long‐term results of a prospective, single‐arm evaluation of everolimus‐eluting bioresorbable vascular scaffolds in infrapopliteal arteries

RL Varcoe, TP Menting, SD Thomas… - Catheterization and …, 2021 - Wiley Online Library
Objectives The aim of this study was to perform a long‐term evaluation of an everolimus
eluting, bioresorbable vascular scaffold (BVS) in the treatment of de novo atherosclerotic …

Evaluation of machine learning methodology for the prediction of healthcare resource utilization and healthcare costs in patients with critical limb ischemia—is …

JS Berger, L Haskell, W Ting, F Lurie, SC Chang… - EPMA Journal, 2020 - Springer
Background Critical limb ischemia (CLI) is a severe stage of peripheral arterial disease and
has a substantial disease and economic burden not only to patients and families, but also to …

Prostanoids for critical limb ischemia: a clinical review and consideration of current guideline recommendations

S Meini, F Dentali, E Melillo, G de Donato… - …, 2020 - journals.sagepub.com
For many years, the only pharmacological option for patients with critical limb ischemia (CLI)
unsuitable for revascularization has been prostanoids; however, some recent guidelines …

Phase Ib safety, two-dose study of MultiGeneAngio in patients with chronic critical limb ischemia

MY Flugelman, M Halak, B Yoffe, J Schneiderman… - Molecular Therapy, 2017 - cell.com
Critical limb ischemia (CLI) is the most severe presentation of peripheral arterial disease.
We developed cell-based therapy entailing intra-arterial injection of autologous venous …