Interleukin-23 (IL-23) is a pro-inflammatory cytokine composed of two subunits, IL-23A (p19)
and IL-12/23B (p40), the latter shared with Interleukin-12 (IL-12). IL-23 is mainly produced …

Klebsiella species cause a wide range of diseases including pneumonia, urinary tract
infections (UTIs), bloodstream infections and sepsis. These infections are particularly a …

Klebsiella pneumoniae causes a wide range of infections, including pneumonias, urinary
tract infections, bacteremias, and liver abscesses. Historically, K. pneumoniae has caused …

The methodology for EPOS2012 has been the same as for the other two productions.
Leaders in the field were invited to critically appraise the literature and write a report on a …

The key role of interleukin-17 (IL-17) and T helper 17 (TH17) cells in tissue inflammation,
autoimmunity and host defence led to the experimental targeting of these molecules in …

Abstract The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A–F, plays
crucial roles in host defense against microbial organisms and in the development of …

Abstract The cytokine interleukin-17 (IL-17) has received considerable attention since the
discovery of a distinct CD4+ T helper (TH) cell subset that produces it, known as the TH17 …

Advancing our understanding of mechanisms of immune regulation in allergy, asthma,
autoimmune diseases, tumor development, organ transplantation, and chronic infections …

Summary Th17 cells, CD4+ T cells that secrete interleukin-17 (IL-17), are pathogenic in
autoimmune diseases and their development and expansion is driven by the cytokines IL-6 …

CD4+ T cells producing interleukin 17 (IL-17) are associated with autoimmunity, although
the precise mechanisms that control their development are undefined. Here we present data …