Shiga toxin (Stx) is one of the most potent bacterial toxins known. Stx is found in Shigella
dysenteriae 1 and in some serogroups of Escherichia coli (called Stx1 in E. coli). In addition …

Cells rely on stress response pathways to uphold cellular homeostasis and limit the negative
effects of harmful environmental stimuli. The stress-and mitogen-activated protein (MAP) …

Ribosome-inactivating proteins (RIPs) are EC3. 2.32. 22 N-glycosidases that recognize a
universally conserved stem-loop structure in 23S/25S/28S rRNA, depurinating a single …

In May 2011, an outbreak caused by Escherichia coli of serotype O104: H4 spread
throughout Germany (1). The next month, France also reported a cluster of E. coli O104: H4 …

Shiga toxins are a group of type 2 ribosome-inactivating proteins (RIPs) produced in several
types of bacteria. The toxins possess an AB 5 structure, which comprises a catalytic A chain …

Shiga toxins comprise a family of structurally and functionally related protein toxins
expressed by Shigella dysenteriae serotype 1 and multiple serotypes of Escherichia coli …

Shiga toxin‐producing bacteria cause widespread outbreaks of bloody diarrhoea that may
progress to life‐threatening systemic complications. Shiga toxins (Stxs), the main virulence …

Shiga toxin 2a (Stx2a) is the virulence factor of Escherichia coli (STEC), which is associated
with hemolytic uremic syndrome, the leading cause of pediatric kidney failure. The A1 …

Ricin belongs to the group of ribosome-inactivating proteins (RIPs), ie, toxins that have
evolved to provide particular species with an advantage over other competitors in nature …

The human ribosomal P complex, which consists of the acidic ribosomal P proteins RPLP0,
RPLP1, and RPLP2 (RPLP proteins), recruits translational factors, facilitating protein …