Bioaccessibility and bioavailability of diet polyphenols and their modulation of gut microbiota

T Lippolis, M Cofano, GR Caponio… - International Journal of …, 2023 - mdpi.com
It is generally accepted that diet-derived polyphenols are bioactive compounds with several
potentially beneficial effects on human health. In general, polyphenols have several …

Nutraceuticals: Focus on anti-inflammatory, anti-cancer, antioxidant properties in gastrointestinal tract

GR Caponio, T Lippolis, V Tutino, I Gigante… - Antioxidants, 2022 - mdpi.com
In recent years, nutraceuticals have gained great popularity, owing to their physiological and
potential health effects, such as anti-inflammatory, anti-cancer, antioxidant, and prebiotic …

The potential of the Mediterranean diet to improve mitochondrial function in experimental models of obesity and metabolic syndrome

M Khalil, H Shanmugam, H Abdallah, JS John Britto… - Nutrients, 2022 - mdpi.com
The abnormal expansion of body fat paves the way for several metabolic abnormalities
including overweight, obesity, and diabetes, which ultimately cluster under the umbrella of …

Anti-proliferative and pro-apoptotic effects of digested aglianico grape pomace extract in human colorectal cancer cells

GR Caponio, M Cofano, T Lippolis, I Gigante… - Molecules, 2022 - mdpi.com
Grape pomace (GP)—the major by-product of winemaking processes—still contains
bioactive molecules with known beneficial properties for human health, such as an …

The potential of Lamiaceae herbs for mitigation of overweight, obesity, and fatty liver: studies and perspectives

F Diab, H Zbeeb, F Baldini, P Portincasa, M Khalil… - Molecules, 2022 - mdpi.com
Numerous plants, plant extracts, and plant-derived compounds are being explored for their
beneficial effects against overweight and liver diseases. Obesity is associated with the …

Probiotic-based bacteriocin: immunity supplementation against viruses. An updated review

M Umair, S Jabbar, L Zhaoxin, Z Jianhao… - Frontiers in …, 2022 - frontiersin.org
Viral infections are a major cause of severe, fatal diseases worldwide. Recently, these
infections have increased due to demanding contextual circumstances, such as …

Influence of Simulated In Vitro Gastrointestinal Digestion on the Phenolic Profile, Antioxidant, and Biological Activity of Thymbra spicata L. Extracts

F Diab, M Khalil, G Lupidi, H Zbeeb, A Salis… - Antioxidants, 2022 - mdpi.com
Plants or plant extracts are widely investigated for preventing/counteracting several chronic
disorders. The oral route is the most common route for nutraceutical and drug administration …

Prevention of oxidative stress and diseases by antioxidant supplementation

G Martemucci, P Portincasa, V Centonze… - Medicinal …, 2023 - ingentaconnect.com
Excessive and uncontrolled oxidative stress can damage biomacromolecules, such as
lipids, proteins, carbohydrates, and DNA, by free radical and oxidant overproduction. In this …

Unveiling antimicrobial and antioxidant compositional differences between Dukkah and Za'atar via SPME-GCMS and HPLC-DAD

MS Sedeek, SM Afifi, MK Mansour, M Hassan… - Molecules, 2022 - mdpi.com
Interest in plant-based diets has been on the rise in recent years owing to the potential
health benefits of their individual components and the notion that plant-based diets might …

The Impact of Za'atar Antioxidant Compounds on the Gut Microbiota and Gastrointestinal Disorders: Insights for Future Clinical Applications

M Khalil, H Abdallah, D Razuka-Ebela, M Calasso… - Antioxidants, 2023 - mdpi.com
Since the gut microbiota plays a pivotal role in host homeostasis and energy balance,
changes in its composition can be associated with disease states through the promotion of …