Versatile and robust genome editing with Streptococcus thermophilus CRISPR1-Cas9

D Agudelo, S Carter, M Velimirovic, A Duringer… - Genome …, 2020 - genome.cshlp.org
Targeting definite genomic locations using CRISPR-Cas systems requires a set of enzymes
with unique protospacer adjacent motif (PAM) compatibilities. To expand this repertoire, we …

ErCas12a CRISPR-MAD7 for model generation in human cells, mice, and rats

Z Liu, JA Schiel, E Maksimova, Ž Strezoska… - The CRISPR …, 2020 - liebertpub.com
MAD7 is an engineered class 2 type VA CRISPR-Cas (Cas12a/Cpf1) system isolated from
Eubacterium rectale. Analogous to Cas9, it is an RNA-guided nuclease with demonstrated …

II 型CRISPR 系统在微生物中的应用.

田艾迪, 刘瑛, 陈叶平, 史海粟… - Journal of Chinese …, 2022 - search.ebscohost.com
摘要CRISPR 系统是-种新兴的基因编辑技术, 是存在于部分细菌中的-种免疫反应系统, 利用Cas
基因编码的蛋白对进入细胞中的外源DNA 进行高效识别并切割, 保护细菌自身免受外源基因 …

[PDF][PDF] DIPARTIMENTO DI MEDICINA CLINICA E SPERIMENTALE DOTTORATO IN BIOMEDICINA TRASLAZIONALE

S STRACQUADANIO - iris.unict.it
The discovery of the penicillin, the first antibiotic, by Alexander Fleming in 1928, and its
introduction in clinical routine in the 1940s to cure bacterial infection, have transformed …

CRISPR-cas9 SYSTEM AND USES THEREOF

Y Doyon - US Patent App. 17/054,008, 2022 - Google Patents
NMEHNETUFHBYEG-IHKSMFQHSA-N TTTN Chemical group C ([C@@ H](C (= O) N
[C@@ H]([C@@ H](C) CC) C (= O) N [C@@ H](CC= 1C= CC (O)= CC= 1) C (= O) N [C …

Two strategies to deepen knowledge the antibiotic resistance related traits in Italian MDR Staphylococci: comparative transcriptomic of two DAP-R/DAP-S MRSA …

S Stracquadanio - 2018 - tesidottorato.depositolegale.it
Antibiotic resistance is worldwide an increasing problem for the public health. Scientists are
working to better know the features of Multi-Drug Resistant (MDR) bacteria to develop new …

[引用][C] 利用内源CRISPR-Cas 系统开展乳酸菌基因编辑的研究进展

朱青, 徐琛, 张书文, 谢宁, 逄晓阳, 吕加平 - 生物工程学报, 2022

[引用][C] ADME-tox prediction and molecular docking studies of two lead flavonoids from the roots of Tephrosia egregia sandw and the gastroprotective effects of its root …

MEF Rogério, HV Chaves, IR Pinto, NA de Sousa… - BIO …, 2022 - Compuscript

[引用][C] Utilizing bacteria-derived components for cancer immunotherapy

C Zhang, Y Mu, Y Zhuo, T Li, FJ Jin, CZ Jin, HG Lee… - Bio Integration, 2022 - Compuscript