Sleep disorders are becoming increasingly common, and their distinct effects on physical
and mental health require elaborate investigation. Gut dysbiosis (GD) has been reported in …

Microglia represent the immune system of the brain. Their role is central in two phenomena,
neuroinflammation and oxidative stress, which are at the roots of different pathologies …

Background Adolescent depression is becoming one of the major public health concerns,
because of its increased prevalence and risk of significant functional impairment and …

The blood–brain barrier, which is formed by tightly interconnected microvascular endothelial
cells, separates the brain from the peripheral circulation. Together with other central nervous …

Lipopolysaccharide (LPS) constitutes much of the surface of Gram-negative bacteria, and if
LPS enters the human body or brain can induce inflammation and act as an endotoxin. We …

Background Latent chronic inflammation has been proposed as a key mediator of multiple
derangements in metabolic syndrome (MetS), which are increasingly becoming recognized …

With the increasing production and demand of plastic products in life, inescapable bisphenol
A (BPA) exposure results in a threat to the health of organisms. Selenium (Se) is an …

Epigenetic regulation is a process that takes place through adaptive cellular pathways
influenced by environmental factors and metabolic changes to modulate gene activity with …

The oil of Torreya grandis (TGO), a common nut in China, is considered to be a bioactive
edible oil and has a great value in functional food development. In this study, the …

Acute ischemic stroke (AIS) remains a major cause of mortality and long-term disability
worldwide, driven by complex and multifaceted etiological factors. Metabolic dysregulation …