Diabetes mellitus (DM) is considered as a main challenge in both developing and
developed countries, as lifestyle has changed and its management seems to be vital. Type I …

Due to advances in understanding the immune microenvironment of colorectal cancer
(CRC), microsatellite classification (dMMR/MSI‐H and pMMR/MSS) has become a key …

Diabetes mellitus (DM), is the most common metabolic disease and is characterized by
sustained hyperglycemia. Accumulating evidences supports a strong association between …

Vitamin B6 may alleviate diabetes by regulating insulin secretion and increasing insulin
sensitivity, but its mechanism remains to be explored. In this study, vitamin B6-mediated …

Epidemiological evidence showed that patients suffering from obesity and T2DM are
significantly at higher risk for chronic low-grade inflammation, oxidative stress, nonalcoholic …

Background Previous studies have shown that T-helper 17 (Th17) cell-related cytokines are
significantly increased in the vitreous of proliferative diabetic retinopathy (PDR), suggesting …

The hedgehog (Hh) signaling pathway is an evolutionarily conserved pathway that regulates
embryonic development in vertebrates. However, strong evidence suggests the role of its …

Childhood obesity is constantly increasing around the world, and it has become a major
public health issue. Considerable evidence indicates that overweight and obesity are …

Extracellular matrix (ECM) stiffness is an important biophysical factor in human bone marrow
mesenchymal stem cells (hBMSCs) differentiation. Although there is evidence that Yes …

Abstract Glycogen synthase kinase 3 (GSK3)-β (GSK3β) interaction protein (GSKIP) is one
of the smallest A-kinase anchoring proteins that possesses a binding site for GSK3β …