The comet assay is a versatile and sensitive method for measuring single-and double-strand
breaks in DNA. The mechanism of formation of comets (under neutral or alkaline conditions) …

Over the past few years, media have popularized the story of the “children of the moon” who
must remain in the dark and avoid exposure to sunlight. 1r3 These children suffer from a rare …

An essential resource for all scientists researching cellular responses to DNA damage.•
Introduces important new material reflective of the major changes and developments that …

Background Several studies have reported associations between radiation toxicity and
single nucleotide polymorphisms (SNPs) in candidate genes. Few associations have been …

The objective of this state of the art paper is to review the mechanisms of induction, the fate,
the methodology, the sensitivity/specificity and predictivity of two major cytogenetic …

The comet assay is the method of choice for measuring DNA damage, of various sorts, in
human cells such as lymphocytes obtained in the course of population-based studies of …

Previous studies have suggested that the frequency of chromosomal aberrations (CAs), but
not of sister chromatid exchanges (SCEs), predicts cancer risk. We have further examined …

Cytogenetic biomarkers have long been applied in surveillance of human genotoxic
exposure and early effects of genotoxic carcinogens. Due to their wide use, it has been …

The frequency of cells with structural chromosomal aberrations (CAs) in peripheral blood
lymphocytes is the first genotoxicity biomarker that has shown an association with cancer …

Soil forms a huge reservoir of nutrients that sustains life on earth. Anthropogenic and natural
impacts have led to degradation of land which declines the overall quality of soil, water or …