Summary Background Long-COVID (LC) encompasses diverse symptoms lasting months
after the initial SARS-CoV-2 infection. Symptoms can be debilitating and affect the quality of …

Cerebral malaria is the most severe neurological complication of infection with Plasmodium
falciparum. With> 575,000 cases annually, children in sub-Saharan Africa are the most …

Background The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular'reactive oxygen species'(ROSs) can exhibit a …

The cytokine erythropoietin (Epo) is tissue-protective in preclinical models of ischemic,
traumatic, toxic, and inflammatory injuries. We have recently characterized Epo derivatives …

Traumatic brain injury and stroke are major causes of mortality and morbidity worldwide.
Unfortunately, almost all phase-III neuroprotective clinical trials for stroke and traumatic brain …

In recent years, much interest has been devoted to defining the role of the IGF system in the
nervous system. The ubiquitous IGFs, their cell membrane receptors, and their carrier …

Acute ischemic stroke is a critical condition that can result in disability and death. The
consequences of this medical condition depend on various factors, including the size of the …

Background: This review summarizes promising approaches for the treatment of traumatic
brain injury (TBI) that are in either preclinical or clinical trials. Objective: The …

Background and Purpose—Erythropoietin (EPO), a hematopoietic growth factor, has been
shown to be neuroprotective when administered as either a pretreatment or posttreatment …

Erythropoietin (Epo) has long been known to be the principal hematopoietic growth factor
that regulates cellular proliferation and differentiation along the erythroid lineage. Recent …