A growing preclinical and clinical body of work on the effects of chronic drug use and drug
addiction has extended the scope of inquiry from the putative reward-related subcortical …

Gambling disorder (GD) was reclassified as a behavioral addiction in the DSM-5 and shares
clinical and behavioral features with substance use disorders (SUDs). Neuroimaging studies …

There have been dramatic changes worldwide in the attitudes toward and consumption of
recreational and medical cannabis. Cannabinoid receptors, which mediate the actions of …

Background The impact of prenatal opioid exposure on brain development remains poorly
understood. Methods We conducted a prospective study of term-born infants with and …

Substance use disorders are associated with neuroimaging abnormalities, but results are
heterogeneous across studies and vary across substances, and the causal interpretation of …

Opioid use in the United States has steadily risen since the 1990s, along with staggering
increases in addiction and overdose fatalities. With this surge in prescription and illicit opioid …

Addiction-like symptoms in relation to excessive and compulsive social media use are
common in the general population. Because they can lead to various adverse effects, there …

Opioid-induced microglia reactivity affects opioid reward and analgesic processes in ways
that may contribute to the neurocognitive impairment observed in opioid addicted …

Background: Research has demonstrated that patients with opioid use disorders (OUD;
including both opioid abuse and/or dependence) have poorer neuropsychological …

Opioid use disorder (OUD) has gained increasing publicity and interest during recent years,
with many countries describing problems of epidemic proportions with regard to opioid use …