The GABA A receptors are the major inhibitory neurotransmitter receptors in mammalian
brain. Each isoform consists of five homologous or identical subunits surrounding a central …

Everyday activity is based on a subtle equilibrium of excitatory and inhibitory neuronal
systems. The most prominent players in neuronal inhibition are synaptic and extrasynaptic …

Fast inhibitory neurotransmission in the brain is principally mediated by the neurotransmitter
GABA (γ-aminobutyric acid) and its synaptic target, the type A GABA receptor (GABAA …

The proper functioning of the adult mammalian brain relies on the orchestrated regulation of
neural activity by a diverse population of GABA (γ-aminobutyric acid)-releasing neurons …

This mini-review attempts to update experimental evidence on the existence of GABAA
receptor pharmacological subtypes and to produce a list of those native receptors that exist …

Cl− channels reside both in the plasma membrane and in intracellular organelles. Their
functions range from ion homeostasis to cell volume regulation, transepithelial transport, and …

GABA-A receptors are the major inhibitory neurotransmitter receptors in the brain and are
the site of action of many clinically important drugs. These receptors are composed of five …

This article does not aim to review in detail the properties of-aminobutyric acidA (GABAA) b
receptors, because recent accounts of that topic are available. In this same journal, a review …

γ-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the vertebrate brain.
In the past, there has been a major research drive focused on the dysfunction of the …

GABA is the principal inhibitory neurotransmitter in the CNS and acts via GABAA and
GABAB receptors. Recently, a novel form of GABAA receptor-mediated inhibition, termed …