Emerging applications of nanotechnology in healthcare systems: Grand challenges and perspectives
Healthcare, as a basic human right, has often become the focus of the development of
innovative technologies. Technological progress has significantly contributed to the …
innovative technologies. Technological progress has significantly contributed to the …
Iron oxide nanoparticles may damage to the neural tissue through iron accumulation, oxidative stress, and protein aggregation
Background In the recent decade, iron oxide nanoparticles (IONPs) have been proposed for
several applications in the central nervous system (CNS), including targeting amyloid beta …
several applications in the central nervous system (CNS), including targeting amyloid beta …
Therapeutic strategies and nano-drug delivery applications in management of ageing Alzheimer's disease
In recent years, the incidental rate of neurodegenerative disorders has increased
proportionately with the aging population. Alzheimer's disease (AD) is one of the most …
proportionately with the aging population. Alzheimer's disease (AD) is one of the most …
Nano carrier drug delivery systems for the treatment of neuropsychiatric disorders: Advantages and limitations
Neuropsychiatric diseases are one of the main causes of disability, affecting millions of
people. Various drugs are used for its treatment, although no effective therapy has been …
people. Various drugs are used for its treatment, although no effective therapy has been …
Current advances in the development of novel polymeric nanoparticles for the treatment of neurodegenerative diseases
A Cano, E Sanchez-Lopez, M Ettcheto… - …, 2020 - Taylor & Francis
Effective intervention is essential to combat the coming epidemic of neurodegenerative (ND)
diseases. Nanomedicine can overcome restrictions of CNS delivery imposed by the blood …
diseases. Nanomedicine can overcome restrictions of CNS delivery imposed by the blood …
Mitigation of amyloidosis with nanomaterials
Amyloidosis is a biophysical phenomenon of protein aggregation with biological and
pathogenic implications. Among the various strategies developed to date, nanomaterials …
pathogenic implications. Among the various strategies developed to date, nanomaterials …
Nanocarrier mediated drug delivery as an impeccable therapeutic approach against Alzheimer's disease
For the past several years, dementia, is one of the predominantly observed groups of
symptoms in a geriatric population. Alzheimer's disease (AD) is a progressive memory …
symptoms in a geriatric population. Alzheimer's disease (AD) is a progressive memory …
Nanomaterials for reducing amyloid cytotoxicity
This review is intended to reflect the recent progress on therapeutic applications of
nanomaterials in amyloid diseases. The progress on anti‐amyloid functions of various …
nanomaterials in amyloid diseases. The progress on anti‐amyloid functions of various …
Oligomers of beta-amyloid protein (Aβ1-42) induce the activation of cyclooxygenase-2 in astrocytes via an interaction with interleukin-1beta, tumour necrosis factor …
I Carrero, MR Gonzalo, B Martin, JM Sanz-Anquela… - Experimental …, 2012 - Elsevier
Despite growing evidence indicating the effects of cytokines, including interleukin-1beta (IL-
1β) and tumour necrosis factor-α (TNFα), and the enzyme cyclooxygenase-2 (COX-2) in …
1β) and tumour necrosis factor-α (TNFα), and the enzyme cyclooxygenase-2 (COX-2) in …
Quercetin conjugated with superparamagnetic iron oxide nanoparticles improves learning and memory better than free quercetin via interacting with proteins involved …
E Amanzadeh, A Esmaeili, REN Abadi… - Scientific reports, 2019 - nature.com
Biomedical application of quercetin (QT) as an effective flavonoid has limitations due to its
low bioavailability. Superparamagnetic iron oxide nanoparticle (SPION) is a novel drug …
low bioavailability. Superparamagnetic iron oxide nanoparticle (SPION) is a novel drug …