Introduction: Toxoplasma gondii is an opportunistic protozoan parasite responsible for
toxoplasmosis. T. gondii is able to infect a wide range of hosts, particularly humans and …

Introduction: Farnesyl pyrophosphate synthase (FPPS) catalyzes the condensation of
isopentenyl diphosphate with dimethylallyl diphosphate to give rise to one molecule of …

As part of our efforts aimed at searching for new antiparasitic agents, 2-alkylmercaptoethyl-1,
1-bisphosphonate derivatives were synthesized and evaluated against Trypanosoma cruzi …

Introduction: Trypanosoma cruzi is the etiologic agent of American trypanosomiasis (Chagas
disease), which is one of the important parasitic diseases worldwide. The number of infected …

Tetraethyl vinylidenebisphosphonate is a versatile synthetic intermediate that allows access
to a variety of highly functionalized compounds bearing the bisphosphonic moiety. As an …

As part of our efforts aimed at searching for new antiparasitic agents, the effect of
representative 2-alkylaminoethyl-1, 1-bisphosphonic acids on Trypanosoma cruzi squalene …

The use of tetraethyl vinylidenebisphosphonate as a dipolarophile in 1, 3-dipolar
cycloaddition reactions was investigated. In particular, the cycloaddition reactions between …