Review of novel potential insulin resistance biomarkers in PCOS patients—The debate is still open

J Kruszewska, H Laudy-Wiaderny… - International journal of …, 2022 - mdpi.com
Research on proteins and peptides that play roles in metabolic regulation, which may be
considered potential insulin resistance markers in some medical conditions, such as …

Role of gremlin-1 in the pathophysiology of the adipose tissues

E Grillo, C Ravelli, G Colleluori, F D'Agostino… - Cytokine & Growth …, 2023 - Elsevier
Gremlin-1 is a secreted bone morphogenetic protein (BMP) antagonist playing a pivotal role
in the regulation of tissue formation and embryonic development. Since its first identification …

Gremlin-1 in pregnancy and postpartum: relation to the fatty liver index, markers of bone health, glucose metabolism and gestational diabetes mellitus status

C Deischinger, M Bastian, K Leitner… - Acta Diabetologica, 2023 - Springer
Introduction Gremlin-1 is a peptide that functions as an antagonist to bone morphogenic
proteins and is overexpressed in obesity and type 2 diabetes mellitus. Gremlin-1 has not yet …

Bone morphogenetic protein 2 inhibits growth differentiation factor 8-induced cell signaling via upregulation of gremlin2 expression in human granulosa-lutein cells

X Luo, HM Chang, Y Yi, Y Sun, PCK Leung - Reproductive Biology and …, 2021 - Springer
Background Bone morphogenetic protein 2 (BMP2), growth differentiation factor 8 (GDF8)
and their functional receptors are expressed in human ovarian follicles, and these two …

The role of asprosin in regulating ovarian granulosa-and theca-cell steroidogenesis: a review with comparisons to other adipokines

ERS Maylem, LF Schütz, LJ Spicer - Reproduction, Fertility and …, 2024 - CSIRO Publishing
Adipose tissues produce a variety of biologically active compounds, including cytokines,
growth factors and adipokines. Adipokines are important as they function as endocrine …

Control of ovarian follicle development by TGF-β family signaling

BK Patton, S Madadi, SA Pangas - Current opinion in endocrine and …, 2021 - Elsevier
The reproductive lifespan of female mammals is limited and ultimately depends on the
production of a sufficient number of high-quality oocytes from a pool of nongrowing …

Screening and identification of key biomarkers associated with endometriosis using bioinformatics and next-generation sequencing data analysis

B Vastrad, C Vastrad - Egyptian Journal of Medical Human Genetics, 2024 - Springer
Background Endometriosis is a common cause of endometrial-type mucosa outside the
uterine cavity with symptoms such as painful periods, chronic pelvic pain, pain with …

[PDF][PDF] Gremlin-1 level in polycystic ovary syndrome and its clinical correlations; A case control study

AM Abdelkarim, AY Rezk… - JPMA. The Journal …, 2023 - pdfs.semanticscholar.org
Objective: To evaluate the involvement of the level of Gremlin-1 in serum and follicular fluid
in the diagnosis of polycystic ovary syndrome. Methods: The case-control study was …

Whole-genome uterine artery transcriptome profiling and alternative splicing analysis in rat pregnancy

K Gopalakrishnan, S Kumar - International Journal of Molecular Sciences, 2020 - mdpi.com
During pregnancy, the uterine artery (UA) undergoes extensive remodeling to permit a 20–
40 fold increase in blood flow with associated changes in the expression of a multitude of …

[PDF][PDF] RECENT ADVANCEMENT IN THE DIAGNOSIS MANAGEMENT AND TREATMENT OF POLYCYSTIC OVARY SYNDROME (PCOS)

U Kuwar, A Kanugo - pharmacy.dypvp.edu.in
Polycystic ovary syndrome (PCOS) is the most popular reproductive, endocrine, and
metabolic disorder affecting several women. This syndrome is marked with infertility or …