Medicinal Effect, In Silico Bioactivity Prediction, and Pharmaceutical Formulation of Ageratum conyzoides L.: A Review

JC Kotta, ABS Lestari, DS Candrasari, M Hariono - Scientifica, 2020 - Wiley Online Library
Goat weed (Ageratum conyzoides L.), or bandotan in Indonesia, is an herbaceous plant that
broadly grows up in both subtropical as well as tropical areas. This herb contains many …

Neutrophil, extracellular matrix components, and their interlinked action in promoting secondary pathogenesis after spinal cord injury

S Dolma, H Kumar - Molecular neurobiology, 2021 - Springer
Secondary pathogenesis following primary mechanical damage to the spinal cord is
believed to be the ultimate reason for the limitation of currently available therapies …

[HTML][HTML] In silico modeling and molecular docking insights of kaempferitrin for colon cancer-related molecular targets

M Govindarasu, S Ganeshan, MA Ansari… - Journal of Saudi …, 2021 - Elsevier
Colorectal cancer is one of the most common cancers worldwide, and it is also one of the
major causes of mortality from cancer. Chemotherapy drugs are generally limited due to …

Bioguided fractionation of local plants against matrix metalloproteinase9 and its cytotoxicity against breast cancer cell models: In silico and in vitro study

M Hariono, R Rollando, J Karamoy, P Hariyono… - Molecules, 2020 - mdpi.com
Matrix metalloproteinase9 (MMP9) is known to be highly expressed during metastatic cancer
where most known potential inhibitors failed in the clinical trials. This study aims to select …

Simultaneous targeting of CD44 and MMP9 catalytic and hemopexin domains as a therapeutic strategy

G Yosef, H Hayun, N Papo - Biochemical Journal, 2021 - portlandpress.com
Crosstalk of the oncogenic matrix metalloproteinase-9 (MMP9) and one of its ligands, CD44,
involves cleavage of CD44 by the MMP9 catalytic domain, with the CD44–MMP9 interaction …

Identification of novel natural product inhibitors against matrix metalloproteinase 9 using quantum mechanical fragment molecular orbital-based virtual screening …

H Lim, H Hong, S Hwang, SJ Kim, SY Seo… - International journal of …, 2022 - mdpi.com
Matrix metalloproteinases (MMPs) are calcium-dependent zinc-containing endopeptidases
involved in multiple cellular processes. Among the MMP isoforms, MMP-9 regulates cancer …

Arylamide as potential selective inhibitor for matrix metalloproteinase 9 (MMP9): design, synthesis, biological evaluation, and molecular modeling

M Hariono, RF Nuwarda, M Yusuf… - Journal of Chemical …, 2019 - ACS Publications
Previous studies have reported that compounds bearing an arylamide linked to a
heterocyclic planar ring have successfully inhibited the hemopexin-like domain (PEX9) of …

Bioguided fractionation of local plants against matrix metalloproteinase9 and its cytotoxicity against breast cancer cell models: In silico and in vitro study (Part II)

M Hariono, R Rollando, I Yoga, A Harjono… - Molecules, 2021 - mdpi.com
In our previous work, the partitions (1 mg/mL) of Ageratum conyzoides (AC) aerial parts and
Ixora coccinea (IC) leaves showed inhibitions of 94% and 96%, respectively, whereas their …

A Review on the Potency of Melaleuca leucadendron Leaves Solid Waste in Wood Preservation and Its In Silico Prediction upon Biological Activities

C Patramurti, R Amin, CMRR Nastiti… - International Journal of …, 2020 - Wiley Online Library
The essential oils from cajuput leaves (Melaleuca leucadendron) have been well‐known
and applied, especially in healthcare management. However, the utilization of the leaves …

ADME, Molecular Targets, Docking and Dynamic Simulation Studies of Phytoconstituents of Cymbopogon citratus (DC.)

II Ajayi, TH Fatoki, AS Alonge, IO Saliu… - …, 2024 - ojs.bonviewpress.com
Abstract Cymbopogon citratus (DC) Stapf., is utilized in both culinary and medicinal contexts,
wherein its extracts demonstrate a range of therapeutic properties, including antidiabetic …