Neuroimaging of mobility in aging: a targeted review
R Holtzer, N Epstein, JR Mahoney… - … Series A: Biomedical …, 2014 - academic.oup.com
Background. The relationship between mobility and cognition in aging is well established,
but the relationship between mobility and the structure and function of the aging brain is …
but the relationship between mobility and the structure and function of the aging brain is …
[HTML][HTML] The neural correlates of discrete gait characteristics in ageing: a structured review
J Wilson, L Allcock, R Mc Ardle, JP Taylor… - Neuroscience & …, 2019 - Elsevier
Gait is complex, described by diverse characteristics underpinned by widespread central
nervous system networks including motor and cognitive functions. Despite this, neural …
nervous system networks including motor and cognitive functions. Despite this, neural …
Slowing gait and risk for cognitive impairment: the hippocampus as a shared neural substrate
AL Rosso, J Verghese, AL Metti, RM Boudreau… - Neurology, 2017 - AAN Enterprises
Objective: To identify the shared neuroimaging signature of gait slowing and cognitive
impairment. Methods: We assessed a cohort of older adults (n= 175, mean age 73 years …
impairment. Methods: We assessed a cohort of older adults (n= 175, mean age 73 years …
Gray matter atrophy distinguishes between Parkinson disease motor subtypes
Objective: To assess differences in gray matter (GM) atrophy between 2 Parkinson disease
(PD) subtypes: the tremor dominant (TD) subtype and the postural instability gait difficulty …
(PD) subtypes: the tremor dominant (TD) subtype and the postural instability gait difficulty …
Longitudinal assessment of global and regional rate of grey matter atrophy in 1,172 healthy older adults: modulation by sex and age
To characterize the neuroanatomical changes in healthy older adults is important to
differentiate pathological from normal brain structural aging. The present study investigated …
differentiate pathological from normal brain structural aging. The present study investigated …
Gait in cerebral small vessel disease, pre-dementia, and dementia: A systematic review
HM Blumen, O Jayakody… - International Journal of …, 2023 - journals.sagepub.com
Background: The interrelationships between gait, cerebral small vessel disease (CSVD),
and cognitive impairments in aging are not well-understood—despite their common co …
and cognitive impairments in aging are not well-understood—despite their common co …
A systematic review of the evidence that brain structure is related to muscle structure and their relationship to brain and muscle function in humans over the lifecourse
AHM Kilgour, OM Todd, JM Starr - BMC geriatrics, 2014 - Springer
Background An association between cognition and physical function has been shown to
exist but the roles of muscle and brain structure in this relationship are not fully understood …
exist but the roles of muscle and brain structure in this relationship are not fully understood …
Associations between mobility, cognition, and brain structure in healthy older adults
Mobility limitations lead to a cascade of adverse events in old age, yet the neural and
cognitive correlates of mobility performance in older adults remain poorly understood. In a …
cognitive correlates of mobility performance in older adults remain poorly understood. In a …
Association between various brain pathologies and gait disturbance
Background: Approximately 30% of older adults have disrupted gait. It is associated with
increased risk of cognitive decline, disability, dementia, and death. Additionally, most older …
increased risk of cognitive decline, disability, dementia, and death. Additionally, most older …
Gray matter volume covariance patterns associated with gait speed in older adults: a multi-cohort MRI study
Accelerated gait decline in aging is associated with many adverse outcomes, including an
increased risk for falls, cognitive decline, and dementia. Yet, the brain structures associated …
increased risk for falls, cognitive decline, and dementia. Yet, the brain structures associated …