Biochemical and mechanical regulation of actin dynamics
Polymerization of actin filaments against membranes produces force for numerous cellular
processes, such as migration, morphogenesis, endocytosis, phagocytosis and organelle …
processes, such as migration, morphogenesis, endocytosis, phagocytosis and organelle …
Bringing structure to cell biology with cryo-electron tomography
Recent advances in cryo-electron microscopy have marked only the beginning of the
potential of this technique. To bring structure into cell biology, the modality of cryo-electron …
potential of this technique. To bring structure into cell biology, the modality of cryo-electron …
[HTML][HTML] Capturing actin assemblies in cells using in situ cryo-electron tomography
J Schneider, M Jasnin - European Journal of Cell Biology, 2022 - Elsevier
Actin contributes to an exceptionally wide range of cellular processes through the assembly
and disassembly of highly dynamic and ordered structures. Visualizing these structures in …
and disassembly of highly dynamic and ordered structures. Visualizing these structures in …
[HTML][HTML] The mammalian endocytic cytoskeleton
A Abouelezz, L Almeida-Souza - European Journal of Cell Biology, 2022 - Elsevier
Clathrin-mediated endocytosis (CME) is the major route through which cells internalise
various substances and recycle membrane components. Via the coordinated action of many …
various substances and recycle membrane components. Via the coordinated action of many …
Mem3DG: modeling membrane mechanochemical dynamics in 3D using discrete differential geometry
Biomembranes adopt varying morphologies that are vital to cellular functions. Many studies
use computational modeling to understand how various mechanochemical factors contribute …
use computational modeling to understand how various mechanochemical factors contribute …
Load adaptation by endocytic actin networks
C Kaplan, SJ Kenny, X Chen… - Molecular biology of …, 2022 - Am Soc Cell Biol
Clathrin-mediated endocytosis (CME) robustness under elevated membrane tension is
maintained by actin assembly–mediated force generation. However, whether more actin …
maintained by actin assembly–mediated force generation. However, whether more actin …
Analysis of functional surfaces on the actin nucleation promoting factor Dip1 required for Arp2/3 complex activation and endocytic actin network assembly
SL Liu, HY Narvaez-Ortiz, M Miner, J Kiemel… - Journal of Biological …, 2022 - ASBMB
Arp2/3 complex nucleates branched actin filaments that drive processes like endocytosis
and lamellipodial protrusion. WISH/DIP/SPIN90 (WDS) proteins form a class of Arp2/3 …
and lamellipodial protrusion. WISH/DIP/SPIN90 (WDS) proteins form a class of Arp2/3 …
Adaptive actin organization buffers endocytosis against changes in membrane tension
C Kaplan, SJ Kenny, S Chen, J Schöneberg, E Sitarska… - BioRxiv, 2020 - biorxiv.org
Clathrin-mediated endocytosis (CME) remains robust despite variation in plasma membrane
tension. Actin assembly-mediated force generation becomes essential for CME under high …
tension. Actin assembly-mediated force generation becomes essential for CME under high …
[PDF][PDF] Mem3DG: Modeling Membrane Mechanochemical Dynamics in 3D using
C Zhu, CT Lee, P Rangamani - scholar.archive.org
Biomembranes adopt varying morphological configurations that are vital to cellular
functions. Many studies 8 use computational modeling to understand how various …
functions. Many studies 8 use computational modeling to understand how various …