Multicomponent reactions (MCRs) are one-pot reactions employing more than two starting
materials, for example, 3, 4,..., 7, where most of the atoms of the starting materials are …

The term functionalized isocyanides refers to all those isocyanides in which a neighbouring
functional group can finely tune the reactivity of the isocyano group or can be exploited in …

The chemistry of heterocyclic carbenes has experienced a rapid development over the last
years. In addition to the imidazolin‐2‐ylidenes, a large number of cyclic diaminocarbenes …

Isocyanide (isonitrile) chemistry began in 1859 when Lieke obtained the first compound of
this type. 1 In 1958, isocyanides became generally available by dehydration of formamides …

Isocyanides have long proved themselves to be irreplaceable building blocks in modern
organic chemistry. The unique features of the isocyano group make isocyanides particularly …

Abstract Die Chemie der heterocyclischen Carbene hat sich in den letzten Jahren stürmisch
entwickelt. Nach den Imidazolin‐2‐ylidenen wurden weitere cyclische Diaminocarbene mit …

More than 60 years have passed since I. Ugi synthesized the first α-amidoamides in one
experimental step involving a combination of aldehydes, amines, carboxylic acids and …

A critical assessment of the OPBE functional is made for its performance for the geometries
and spin-states of iron complexes. In particular, we have examined its performance for the …

Screening of large and diverse libraries is the 'bread and butter'in the first phase of the
discovery of novel drugs. However, maintenance and periodic renewal of high-quality large …

Three-component reactions have emerged as useful methods because the combination of
three components to generate new products in a single step is extremely economical …