Label-free optical imaging employs natural and non-destructive approaches to visualize
biomedical samples for both biological assays and clinical diagnosis. At present, this field …

There are many morphological transformations during development of human embryos that
mainly involve phenomena that can be easily assessed in living embryos by simple non …

Fundamentals of Light Microscopy and Electronic Imaging, Second Edition provides a
coherent introduction to the principles and applications of the integrated optical microscope …

BACKGROUND: Spindles are formed from microtubules and are exquisitely sensitive to
changes in temperature. An orientation-independent polarized light microscope, the …

The female gamete plays a crucial role in determining embryo competence and therefore in
vitro fertilization (IVF) results. Oocyte quality is not only influenced by the nuclear and …

BACKGROUND: Birefringent spindles imaged with the Polscope can predict fertilization
rates after intracytoplasmic sperm injection (ICSI). The present study examined the …

Polarized light microscopy provides unique opportunities for analyzing the molecular order
in man-made and natural materials, including biological structures inside living cells …

This study assesses meiotic spindle and zona pellucida characteristics using the PolScope,
and analyses their relationship to embryonic development potential. A total of 205 matured …

BACKGROUND Birefrigent meiotic spindle in live human oocytes can be visualized by the
PolScope. This study investigated the relationship between birefrigent meiotic spindle and …

Factors affecting the efficiency of animal cloning remain to be elucidated 1, 2. Enucleation of
recipient oocytes is a critical step in cloning procedures and typically is performed by …