dbCAN3: automated carbohydrate-active enzyme and substrate annotation

J Zheng, Q Ge, Y Yan, X Zhang, L Huang… - Nucleic Acids …, 2023 - academic.oup.com
Carbohydrate active enzymes (CAZymes) are made by various organisms for complex
carbohydrate metabolism. Genome mining of CAZymes has become a routine data analysis …

Profiling the human intestinal environment under physiological conditions

D Shalon, RN Culver, JA Grembi, J Folz, PV Treit, H Shi… - Nature, 2023 - nature.com
The spatiotemporal structure of the human microbiome,, proteome and metabolome, reflects
and determines regional intestinal physiology and may have implications for disease. Yet …

[HTML][HTML] Gut-microbiota-targeted diets modulate human immune status

HC Wastyk, GK Fragiadakis, D Perelman, D Dahan… - Cell, 2021 - cell.com
Diet modulates the gut microbiome, which in turn can impact the immune system. Here, we
determined how two microbiota-targeted dietary interventions, plant-based fiber and …

dbCAN2: a meta server for automated carbohydrate-active enzyme annotation

H Zhang, T Yohe, L Huang, S Entwistle… - Nucleic acids …, 2018 - academic.oup.com
Complex carbohydrates of plants are the main food sources of animals and microbes, and
serve as promising renewable feedstock for biofuel and biomaterial production …

Genomic and functional analyses of fungal and bacterial consortia that enable lignocellulose breakdown in goat gut microbiomes

X Peng, SE Wilken, TS Lankiewicz, SP Gilmore… - Nature …, 2021 - nature.com
The herbivore digestive tract is home to a complex community of anaerobic microbes that
work together to break down lignocellulose. These microbiota are an untapped resource of …

The 2022 Nucleic Acids Research database issue and the online molecular biology database collection

DJ Rigden, XM Fernández - Nucleic acids research, 2022 - academic.oup.com
Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …

dbCAN-seq update: CAZyme gene clusters and substrates in microbiomes

J Zheng, B Hu, X Zhang, Q Ge, Y Yan… - Nucleic Acids …, 2023 - academic.oup.com
C arbohydrate A ctive En Zymes (CAZymes) are significantly important for microbial
communities to thrive in carbohydrate rich environments such as animal guts, agricultural …

Division of labor in honey bee gut microbiota for plant polysaccharide digestion

H Zheng, J Perreau, JE Powell, B Han… - Proceedings of the …, 2019 - National Acad Sciences
Bees acquire carbohydrates from nectar and lipids; and amino acids from pollen, which also
contains polysaccharides including cellulose, hemicellulose, and pectin. These potential …

Microbiomes in the Challenger Deep slope and bottom-axis sediments

YL Zhou, P Mara, GJ Cui, VP Edgcomb… - Nature communications, 2022 - nature.com
Hadal trenches are the deepest and most remote regions of the ocean. The 11-kilometer
deep Challenger Deep is the least explored due to the technical challenges of sampling …

Mediterranean grassland soil C–N compound turnover is dependent on rainfall and depth, and is mediated by genomically divergent microorganisms

S Diamond, PF Andeer, Z Li, A Crits-Christoph… - Nature …, 2019 - nature.com
Soil microbial activity drives the carbon and nitrogen cycles and is an important determinant
of atmospheric trace gas turnover, yet most soils are dominated by microorganisms with …