Centromeres are the eukaryotic chromosomal sites at which the kinetochore forms and
attaches to spindle microtubules to orchestrate chromosomal segregation in mitosis and …

Centromeres are essential loci in eukaryotes that are necessary for the faithful segregation
of chromosomes in mitosis and meiosis. Centromeres organize the kinetochore, the protein …

Repeat-enriched genomic regions evolve rapidly and yet support strictly conserved
functions like faithful chromosome transmission and the preservation of genome integrity …

The fruit fly Drosophila melanogaster serves as a powerful model organism for advancing
our understanding of biological processes, not just by studying its similarities with other …

The aim of mitosis is to segregate duplicated chromosomes equally into daughter cells
during cell division. Meiosis serves a similar purpose, but additionally separates …

The fact that satellite DNAs (satDNAs) in eukaryotes are abundant genomic components,
can perform functional roles, but can also change rapidly across species while being …

Despite their essential role in chromosome segregation in most eukaryotes, centromeric
histones (CenH3s) evolve rapidly and are subject to gene turnover. We previously identified …

The centromere is a specialized chromatin region that is critical for faithful chromosome
segregation. Centromere function is conferred epigenetically, by the presence of a histone …