HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide
S Wang, F Matassoli, B Zhang, T Liu, CH Shen… - Cell reports, 2023 - cell.com
Elicitation of antibodies that neutralize the tier-2 neutralization-resistant isolates that typify
HIV-1 transmission has been a long-sought goal. Success with prefusion-stabilized …
HIV-1 transmission has been a long-sought goal. Success with prefusion-stabilized …
Bispecific antibody CAP256. J3LS targets V2-apex and CD4-binding sites with high breadth and potency
ABSTRACT Antibody CAP256-VRC26. 25 targets the second hypervariable region (V2) at
the apex of the HIV envelope (Env) trimer with extraordinary neutralization potency, although …
the apex of the HIV envelope (Env) trimer with extraordinary neutralization potency, although …
Conformational dynamics of α‐1 acid glycoprotein (AGP) in cancer: A comparative study of glycosylated and unglycosylated AGP
Abstract α‐1 acid glycoprotein (AGP) is one of the most abundant plasma proteins. It fulfills
two important functions: immunomodulation, and binding to various drugs and receptors …
two important functions: immunomodulation, and binding to various drugs and receptors …
GLYCO: a tool to quantify glycan shielding of glycosylated proteins
Motivation Glycans play important roles in protein folding and cell–cell interactions—and,
furthermore, glycosylation of protein antigens can dramatically impact immune responses …
furthermore, glycosylation of protein antigens can dramatically impact immune responses …