Clinical development of metal complexes as photosensitizers for photodynamic therapy of cancer

J Karges - Angewandte chemie international edition, 2022 - Wiley Online Library
Cancer has emerged over the last decades as one of the deadliest diseases in the world.
Among the most commonly used techniques (ie surgery, immunotherapy, radiotherapy or …

Oncologic photodynamic therapy: basic principles, current clinical status and future directions

D Van Straten, V Mashayekhi, HS De Bruijn, S Oliveira… - Cancers, 2017 - mdpi.com
Photodynamic therapy (PDT) is a clinically approved cancer therapy, based on a
photochemical reaction between a light activatable molecule or photosensitizer, light, and …

[HTML][HTML] An updated overview on the development of new photosensitizers for anticancer photodynamic therapy

J Zhang, C Jiang, JPF Longo, RB Azevedo… - … pharmaceutica sinica B, 2018 - Elsevier
Photodynamic therapy (PDT), based on the photoactivation of photosensitizers (PSs), has
become a well-studied therapy for cancer. Photofrin®, belonging to the first generation of …

Photodynamic therapy (PDT) of cancer: from local to systemic treatment

JM Dąbrowski, LG Arnaut - Photochemical & Photobiological Sciences, 2015 - pubs.rsc.org
Photodynamic therapy (PDT) requires a medical device, a photosensitizing drug and
adequate use of both to trigger biological mechanisms that can rapidly destroy the primary …

Recent studies in photodynamic therapy for cancer treatment: From basic research to clinical trials

TE Kim, JE Chang - Pharmaceutics, 2023 - mdpi.com
Photodynamic therapy (PDT) is an emerging and less invasive treatment modality for
various types of cancer. This review provides an overview of recent trends in PDT research …

Photodynamic therapy of cancer: an update

P Agostinis, K Berg, KA Cengel… - CA: a cancer journal …, 2011 - Wiley Online Library
Photodynamic therapy (PDT) is a clinically approved, minimally invasive therapeutic
procedure that can exert a selective cytotoxic activity toward malignant cells. The procedure …

Porphyrin and nonporphyrin photosensitizers in oncology: preclinical and clinical advances in photodynamic therapy

AE O'Connor, WM Gallagher… - Photochemistry and …, 2009 - Wiley Online Library
Photodynamic therapy (PDT) is now a well‐recognized modality for the treatment of cancer.
While PDT has developed progressively over the last century, great advances have been …

Oncologic photodynamic therapy photosensitizers: a clinical review

RR Allison, CH Sibata - Photodiagnosis and photodynamic therapy, 2010 - Elsevier
A myriad of naturally occurring and synthetic structures are capable of transferring the
energy of light. Few, however, allow for this energy transfer to enable a type II photochemical …

Animal models and therapeutic molecular targets of cancer: utility and limitations

M Cekanova, K Rathore - Drug design, development and therapy, 2014 - Taylor & Francis
Cancer is the term used to describe over 100 diseases that share several common
hallmarks. Despite prevention, early detection, and novel therapies, cancer is still the …

Ferritin nanocages to encapsulate and deliver photosensitizers for efficient photodynamic therapy against cancer

Z Zhen, W Tang, C Guo, H Chen, X Lin, G Liu, B Fei… - ACS …, 2013 - ACS Publications
Photodynamic therapy is an emerging treatment modality that is under intensive preclinical
and clinical investigations for many types of disease including cancer. Despite the promise …