Anemia is common and associated with adverse outcomes in children with chronic kidney
disease (CKD). Many factors contribute to declining hemoglobin as CKD progresses, but …

PEGylation is the technology involving the covalent attachment of polyethylene glycol (PEG)
to a protein‐, peptide‐or small‐molecule drug to improve their pharmacokinetic …

Renal anemia is a complication of chronic kidney disease. Guidelines for safe and effective
treatment in patients with renal anemia are needed. The Japanese Society for Dialysis …

Covalent attachment of therapeutic proteins to polyethylene glycol (PEG) is widely used for
the improvement of its pharmacokinetic and pharmacological properties, as well as the …

Erythropoiesis-stimulating agents (ESAs) have become a hallmark of anaemia therapy in
patients with chronic kidney disease (CKD). Although different ESAs are available for the …

Commended in the Haematology category at the British MedicalAssociation Book Awards
2008 This unique and practical book introduces the reader to theconcept of blood …

Anemia management is an important component of the care provided to children with
chronic kidney disease (CKD) and influences both morbidity and mortality risk. The …

Results A total of 64 patients were enrolled. A conversion factor (4 µg every 4 weeks for
each weekly dose of 125 IU epoetin alfa/beta or 0.55 µg darbepoetin) was identified that …

Background: Anemia is a prevalent situation in patients with chronic kidney disease (CKD)
and can be well managed with erythropoiesis-stimulating agents (ESAs). Continuous …

Rationale & Objective The optimum starting dose of intravenous continuous erythropoietin
receptor activator (CERA) has been previously determined; this study ascertains the …