Neuro–bone tissue engineering: emerging mechanisms, potential strategies, and current challenges

W Sun, B Ye, S Chen, L Zeng, H Lu, Y Wan, Q Gao… - Bone Research, 2023 - nature.com
The skeleton is a highly innervated organ in which nerve fibers interact with various skeletal
cells. Peripheral nerve endings release neurogenic factors and sense skeletal signals …

The role of sensory and sympathetic nerves in craniofacial bone regeneration

F Assefa - Neuropeptides, 2023 - Elsevier
Multiple factors regulate the regeneration of craniofacial bone defects. The nervous system
is recognized as one of the critical regulators of bone mass, thereby suggesting a role for …

Photoluminescent carbon dots (PCDs) from sour apple: a biocompatible nanomaterial for preventing UHMWPE wear-particle induced osteolysis via modulating …

X Li, Y Lu, J Li, S Zhou, Y Wang, L Li, F Zhao - Journal of …, 2022 - Springer
Photoluminescent nanomaterials have been widely employed in several biological
applications both in vitro and in vivo. For the first time, we report a novel application of sour …

Sympathetic Neurotransmitter, VIP, Delays Intervertebral Disc Degeneration via FGF18/FGFR2‐Mediated Activation of Akt Signaling Pathway

K Sun, J Sun, C Yan, J Sun, X Xu, J Shi - Advanced Biology, 2024 - Wiley Online Library
Neuromodulation‐related intervertebral disc degeneration (IVDD) is a novel IVDD pattern
and are proposed recently. However, the mechanistic basis of neuromodulation and …

Study on optimizing novel antimicrobial peptides with bifunctional activity to prevent and treat peri-implant disease

S Yu, Q Zhang, M Hu, B Zhao, Z Liu, C Li, X Zhang - Antibiotics, 2022 - mdpi.com
The bacterial invasions and inflammatory responses after implant placement often affect
osseointegration; the increased secretion of pro-inflammatory cytokines can lead to poor …

[HTML][HTML] Evaluating a Venom-Bioinspired Peptide, NOR-1202, as an Antiepileptic Treatment in Male Mice Models

MVT Quintanilha, GAM Gobbo, GB Pinheiro… - Toxins, 2024 - mdpi.com
Epilepsy, a neurological disorder characterized by excessive neuronal activity and
synchronized electrical discharges, ranks among the most prevalent global neurological …

The neuropeptide VIP limits human osteoclastogenesis: clinical associations with bone metabolism markers in patients with early arthritis

D Castro-Vazquez, A Lamana, P Arribas-Castaño… - Biomedicines, 2021 - mdpi.com
We aimed to evaluate the direct action of VIP on crucial molecules involved in human
osteoclast differentiation and function. We also investigated the relationship between VIP …

[HTML][HTML] Emerging pharmacological targets for alcohol use disorder

DF Brockway, NA Crowley - Alcohol, 2024 - Elsevier
ABSTRACT Alcohol Use Disorder (AUD) remains a challenging condition with limited
effective treatment options; however new technology in drug delivery and advancements in …

The Non-Erythropoietic EPO Analogue Cibinetide Inhibits Osteoclastogenesis In Vitro and Increases Bone Mineral Density in Mice

Z Awida, A Bachar, H Saed, A Gorodov… - International Journal of …, 2021 - mdpi.com
The two erythropoietin (EPO) receptor forms mediate different cellular responses to
erythropoietin. While hematopoiesis is mediated via the homodimeric EPO receptor (EPOR) …