How effective are antidepressants for depression over the long term? A critical review of relapse prevention trials and the issue of withdrawal confounding

MP Hengartner - Therapeutic advances in …, 2020 - journals.sagepub.com
The aim of this article is to discuss the validity of relapse prevention trials and the issue of
withdrawal confounding in these trials. Recommendations for long-term antidepressant …

First do no harm: interventions during childbirth

L Jansen, M Gibson, BC Bowles… - The Journal of …, 2013 - connect.springerpub.com
An online survey was completed by 1,829 New Zealand adults prescribed antidepressants.
Only 43% were experiencing self-reported “severe” depression when first prescribed …

The role of Facebook groups in the management and raising of awareness of antidepressant withdrawal: is social media filling the void left by health services?

E White, J Read, S Julo - Therapeutic advances in …, 2021 - journals.sagepub.com
Background: Antidepressant withdrawal is experienced by about half of people who try to
reduce or come off their medication. It can be a debilitating, long lasting process. Many …

[HTML][HTML] Designing withdrawal support services for antidepressant users: patients' views on existing services and what they really need

J Read, J Moncrieff, MA Horowitz - Journal of Psychiatric Research, 2023 - Elsevier
Abstract Background Public Health England has recommended that services be put in place
to support people who choose to withdraw from antidepressants because of a current gap …

Psychological mechanisms and functions of 5-HT and SSRIs in potential therapeutic change: Lessons from the serotonergic modulation of action selection, learning …

C Roberts, BJ Sahakian, TW Robbins - Neuroscience & biobehavioral …, 2020 - Elsevier
Uncertainty regarding which psychological mechanisms are fundamental in mediating SSRI
treatment outcomes and wide-ranging variability in their efficacy has raised more questions …

How user knowledge of psychotropic drug withdrawal resulted in the development of person-specific tapering medication

PC Groot, J van Os - Therapeutic advances in …, 2020 - journals.sagepub.com
Coming off psychotropic drugs can cause physical as well as mental withdrawal, resulting in
failed withdrawal attempts and unnecessary long-term drug use. The first reports about …

Outcome of antidepressant drug discontinuation with taperingstrips after 1–5 years

PC Groot, J van Os - Therapeutic advances in …, 2020 - journals.sagepub.com
Background: Stopping antidepressants is often difficult due to withdrawal. Taperingstrips
were developed to facilitate antidepressant discontinuation according to the recently …

[HTML][HTML] The need for antidepressant withdrawal support services: recommendations from 708 patients

J Read, S Lewis, M Horowitz, J Moncrieff - Psychiatry Research, 2023 - Elsevier
Approximately half of the tens of millions of people currently taking antidepressants will
experience withdrawal symptoms when they try to reduce or come off them. Nearly half of …

Antidepressant tapering is not routine but could be

J Phelps, J Nguyen, OP Coskey - The Journal of the …, 2023 - Am Board Family Med
Introduction: When antidepressants are discontinued, severe withdrawal symptoms are
possible. Some patients have few or no problems stopping, whereas others struggle. That …

Designing flexible longitudinal regimens: Supporting clinician planning for discontinuation of psychiatric drugs

E Jo, M Ryu, G Kenderova, S So, B Shapiro… - Proceedings of the …, 2022 - dl.acm.org
Clinical decision support tools have typically focused on one-time support for diagnosis or
prognosis, but have the ability to support providers in longitudinal planning of patient care …