While cancer cell proliferation depends on access to extracellular nutrients, inadequate
tumour perfusion means that glucose, amino acids and lipids are often in short supply. To …

Nanoparticles (NP) are attractive options for the therapeutic delivery of active
pharmaceutical drugs, proteins and nucleic acids into cells, tissues and organs. Research …

This article aims at providing an update on the complexity of clathrin-independent
endocytosis. It is now almost 30 years since we first wrote a review about its existence; at …

Phagocytosis is a specialized process that enables cellular ingestion and clearance of
microbes, dead cells and tissue debris that are too large for other endocytic routes. As such …

In the drug delivery field, there is beyond doubt that the shape of micro-and nanoparticles
(M&NPs) critically affects their biological fate. Herein, following an introduction describing …

In macropinocytosis, cells take up micrometre-sized droplets of medium into internal
vesicles. These vesicles are acidified and fused to lysosomes, their contents digested and …

Macropinocytosis is increasingly recognized for its versatile adaptations and functions as a
highly conserved, ubiquitous pathway for the bulk uptake of fluid, particulate cargo, and …

The soil-dwelling social amoeba Dictyostelium discoideum feeds on bacteria. Each meal is
a potential infection because some bacteria have evolved mechanisms to resist predation …

Macropinocytosis is an important mechanism of internalizing extracellular materials and
dissolved molecules in eukaryotic cells. Macropinocytosis has a dual effect on cancer cells …

There is a growing appreciation that the direct interaction between bacteriophages and the
mammalian host can facilitate diverse and unexplored symbioses. Yet the impact these …