The role of Epstein–Barr virus in nasopharyngeal carcinoma

ZY Su, PY Siak, CO Leong, SC Cheah - Frontiers in Microbiology, 2023 - frontiersin.org
Nasopharyngeal carcinoma (NPC) is a metastasis-prone malignancy closely associated
with the Epstein–Barr virus (EBV). Despite ubiquitous infection of EBV worldwide, NPC …

The role of EBV-encoded LMP1 in the NPC tumor microenvironment: from function to therapy

AKF Lo, CW Dawson, HL Lung, KL Wong… - Frontiers in …, 2021 - frontiersin.org
Nasopharyngeal carcinoma (NPC) is closely associated with Epstein-Barr virus (EBV)
infection. It is also characterized by heavy infiltration with non-malignant leucocytes. The …

Targeting Epstein-Barr virus in nasopharyngeal carcinoma

PM Hau, HL Lung, M Wu, CM Tsang, KL Wong… - Frontiers in …, 2020 - frontiersin.org
Nasopharyngeal carcinoma (NPC) is consistently associated with Epstein-Barr virus (EBV)
infection in regions in which it is endemic, including Southern China and Southeast Asia …

Cumulative roles for Epstein-Barr virus, human endogenous retroviruses, and human herpes virus-6 in driving an inflammatory cascade underlying MS pathogenesis

UC Meier, RC Cipian, A Karimi, R Ramasamy… - Frontiers in …, 2021 - frontiersin.org
Roles for viral infections and aberrant immune responses in driving localized
neuroinflammation and neurodegeneration in multiple sclerosis (MS) are the focus of …

Dual‐targeting peptide‐guided approach for precision delivery and cancer monitoring by using a safe upconversion nanoplatform

S Zha, HF Chau, WY Chau, LS Chan, J Lin… - Advanced …, 2021 - Wiley Online Library
Abstract Using Epstein‐Barr virus (EBV)‐induced cancer cells and HeLa cells as a
comparative study model, a novel and safe dual‐EBV‐oncoproteins‐targeting pH …

Polymeric dendrimers as nanocarrier vectors for neurotheranostics

H Li, S Zha, H Li, H Liu, KL Wong, AH All - Small, 2022 - Wiley Online Library
Dendrimers are polymers with well‐defined 3D branched structures that are vastly utilized in
various neurotheranostics and biomedical applications, particularly as nanocarrier vectors …

[HTML][HTML] EBV latent membrane protein 1 augments γδ T cell cytotoxicity against nasopharyngeal carcinoma by induction of butyrophilin molecules

Y Liu, KS Lui, Z Ye, TY Fung, L Chen, PY Sit… - Theranostics, 2023 - ncbi.nlm.nih.gov
Nasopharyngeal carcinoma (NPC) is a diverse cancer with no well-defined tumor antigen,
associated with oncogenic Epstein-Barr Virus (EBV), and with usually late-stage diagnosis …

EBNA1 inhibitors block proliferation of spontaneous lymphoblastoid cell lines from patients with multiple sclerosis and healthy controls

MCG Monaco, SS Soldan, C Su, A Clauze… - Neurology …, 2023 - AAN Enterprises
Background and Objectives Epstein-Barr virus (EBV) is a ubiquitous herpesvirus that
establishes lifelong latency in memory B cells and has been identified as a major risk factor …

Lytic induction therapy Against Epstein–Barr virus-associated malignancies: Past, present, and future

SPT Yiu, M Dorothea, KF Hui, AKS Chiang - Cancers, 2020 - mdpi.com
Epstein–Barr virus (EBV) lytic induction therapy is an emerging virus-targeted therapeutic
approach that exploits the presence of EBV in tumor cells to confer specific killing effects …

Targeting Epstein–Barr virus in multiple sclerosis: when and how?

G Giovannoni - Current Opinion in Neurology, 2024 - journals.lww.com
EBV is the probable cause of MS and is likely to be driving MS disease activity via latent-lytic
infection cycling. There is evidence that all licensed MS disease-modifying therapies target …