[HTML][HTML] The long and short non-coding RNAs modulating EZH2 signaling in cancer

S Mirzaei, MH Gholami, K Hushmandi… - Journal of hematology & …, 2022 - Springer
Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in
encoding proteins. However, they participate in developmental and biological processes …

[HTML][HTML] Recent advances in understanding the pathogenesis of rheumatoid arthritis: new treatment strategies

AL Mueller, Z Payandeh, N Mohammadkhani… - Cells, 2021 - mdpi.com
Rheumatoid arthritis (RA) is considered a chronic systemic, multi-factorial, inflammatory, and
progressive autoimmune disease affecting many people worldwide. While patients show …

Nrf2 signaling pathway in cisplatin chemotherapy: Potential involvement in organ protection and chemoresistance

S Mirzaei, AT Mohammadi, MH Gholami… - Pharmacological …, 2021 - Elsevier
Nuclear factor erythroid 2-related factor 2 (Nrf2) is a vital transcription factor and its induction
is of significant importance for protecting against oxidative damage. Increased levels of …

[HTML][HTML] Flavonoids as an effective sensitizer for anti-cancer therapy: Insights into multi-faceted mechanisms and applicability towards individualized patient profiles

A Liskova, M Samec, L Koklesova, A Brockmueller… - Epma Journal, 2021 - Springer
Cost-efficacy of currently applied treatments is an issue in overall cancer management
challenging healthcare and causing tremendous economic burden to societies around the …

Natural antioxidant compounds as potential pharmaceutical tools against neurodegenerative diseases

A Marino, M Battaglini, N Moles, G Ciofani - ACS omega, 2022 - ACS Publications
Natural antioxidants are a very large diversified family of molecules classified by activity
(enzymatic or nonenzymatic), chemical-physical properties (eg, hydrophilic or lipophilic) …

Curcumin–cisplatin chemotherapy: A novel strategy in promoting chemotherapy efficacy and reducing side effects

Y Hussain, L Islam, H Khan, R Filosa… - Phytotherapy …, 2021 - Wiley Online Library
The efficacy of chemotherapy in cancer therapy is limited due to resistance, treatment
selectivity, and severe adverse effects. Immunotherapy, chemotherapy, targeted therapy …

[HTML][HTML] Elucidating role of reactive oxygen species (ROS) in cisplatin chemotherapy: a focus on molecular pathways and possible therapeutic strategies

S Mirzaei, K Hushmandi, A Zabolian, H Saleki… - Molecules, 2021 - mdpi.com
The failure of chemotherapy is a major challenge nowadays, and in order to ensure effective
treatment of cancer patients, it is of great importance to reveal the molecular pathways and …

Employing siRNA tool and its delivery platforms in suppressing cisplatin resistance: approaching to a new era of cancer chemotherapy

S Mirzaei, MH Gholami, F Hashemi, A Zabolian… - Life Sciences, 2021 - Elsevier
Although chemotherapy is a first option in treatment of cancer patients, drug resistance has
led to its failure, requiring strategies to overcome it. Cancer cells are capable of switching …

Brain delivery of curcumin through low-intensity ultrasound-induced blood–brain barrier opening via lipid-plga nanobubbles

Y Yan, Y Chen, Z Liu, F Cai, W Niu, L Song… - International Journal …, 2021 - Taylor & Francis
Background Parkinson's disease (PD) is a progressive neurodegenerative disorder. Owing
to the presence of blood–brain barrier (BBB), conventional pharmaceutical agents are …

The role of microRNA-338-3p in cancer: growth, invasion, chemoresistance, and mediators

S Mirzaei, A Zarrabi, SE Asnaf, F Hashemi, A Zabolian… - Life sciences, 2021 - Elsevier
Cancer still remains as one of the leading causes of death worldwide. Metastasis and
proliferation are abnormally increased in cancer cells that subsequently, mediate resistance …