The scientific community is increasingly concerned with the proportion of published
“discoveries” that are not replicated in subsequent studies. The field of rodent behavioral …

Many modern human genomes retain DNA inherited from interbreeding with archaic
hominins, such as Neandertals, yet the influence of this admixture on human traits is largely …

The reproducibility of statistical findings has become a concern not only for statisticians, but
for all researchers engaged in empirical discovery. Section 2 of this article identifies key …

The storage of hydrogen in materials has received a significant amount of attention in recent
years because this approach is widely thought to be one of the most promising solutions to …

Background—PCSK9 loss-of-function (LOF) variants allow for the examination of the effects
of lifetime reduced low-density lipoprotein cholesterol (LDL-C) on cardiovascular events. We …

With the ever growing amount of textual data from a large variety of languages, domains,
and genres, it has become standard to evaluate NLP algorithms on multiple datasets in …

Two-sample multiple testing has a wide range of applications. The conventional practice first
reduces the original observations to a vector of p-values and then chooses a cut-off to adjust …

Determining if specific cell type (s) are responsible for an association between DNA
methylation (DNAm) and a given phenotype is important for understanding the biological …

This article considers replicability of the performance of predictors across studies. We
suggest a general approach to investigating this issue, based on ensembles of prediction …

Platelets play an essential role in hemostasis and thrombosis. We performed a genome-
wide association study of platelet count in 12,491 participants of the Hispanic Community …