COVID-19 and diabetes: understanding the interrelationship and risks for a severe course
CP Landstra, EJP de Koning - Frontiers in endocrinology, 2021 - frontiersin.org
The relationship between COVID-19 and diabetes mellitus is complicated and bidirectional.
On the one hand, diabetes mellitus is considered one of the most important risk factors for a …
On the one hand, diabetes mellitus is considered one of the most important risk factors for a …
[HTML][HTML] Diabetes, infection risk and COVID-19
S Erener - Molecular metabolism, 2020 - Elsevier
Background Individuals with diabetes are at a greater risk of hospitalization and mortality
resulting from viral, bacterial, and fungal infections. The coronavirus disease-2019 (COVID …
resulting from viral, bacterial, and fungal infections. The coronavirus disease-2019 (COVID …
Diabetes primes neutrophils to undergo NETosis, which impairs wound healing
Wound healing is impaired in diabetes, resulting in significant morbidity and mortality.
Neutrophils are the main leukocytes involved in the early phase of healing. As part of their …
Neutrophils are the main leukocytes involved in the early phase of healing. As part of their …
Fracture healing under healthy and inflammatory conditions
L Claes, S Recknagel, A Ignatius - Nature Reviews Rheumatology, 2012 - nature.com
Optimal fracture treatment requires knowledge of the complex physiological process of bone
healing. The course of bone healing is mainly influenced by fracture fixation stability …
healing. The course of bone healing is mainly influenced by fracture fixation stability …
New insights into neutrophil extracellular traps: mechanisms of formation and role in inflammation
H Yang, MH Biermann, JM Brauner, Y Liu… - Frontiers in …, 2016 - frontiersin.org
Recent data suggest that NETosis plays a crucial role in the innate immune response and
disturbs the homeostasis of the immune system. NETosis is a form of neutrophil-specific cell …
disturbs the homeostasis of the immune system. NETosis is a form of neutrophil-specific cell …
IL-1β implications in type 1 diabetes mellitus progression: systematic review and meta-analysis
F Cano-Cano, L Gómez-Jaramillo… - Journal of clinical …, 2022 - mdpi.com
During Type 1 Diabetes Mellitus (T1DM) progression, there is chronic and low-grade
inflammation that could be related to the evolution of the disease. We carried out a …
inflammation that could be related to the evolution of the disease. We carried out a …
Obesity and insulin resistance: associations with chronic inflammation, genetic and epigenetic factors
A Gasmi, S Noor, A Menzel, L Pivina… - Current medicinal …, 2021 - ingentaconnect.com
Background: Obesity is known to be a multifactorial disease. In its pathogenesis, different
factors such as chronic inflammation, oxidative stress, insulin resistance, genetic factors …
factors such as chronic inflammation, oxidative stress, insulin resistance, genetic factors …
[HTML][HTML] Peptidylarginine deiminase 4: a nuclear button triggering neutrophil extracellular traps in inflammatory diseases and aging
Abstract Peptidylarginine deiminase 4 (PAD4) is a nuclear citrullinating enzyme that is
critically involved in the release of decondensed chromatin from neutrophils as neutrophil …
critically involved in the release of decondensed chromatin from neutrophils as neutrophil …
[HTML][HTML] Vitiligo-inducing phenols activate the unfolded protein response in melanocytes resulting in upregulation of IL6 and IL8
Vitiligo is characterized by depigmented skin patches caused by loss of epidermal
melanocytes. Oxidative stress may have a role in vitiligo onset, while autoimmunity …
melanocytes. Oxidative stress may have a role in vitiligo onset, while autoimmunity …
Low-grade inflammation in type 2 diabetes: a cross-sectional study from a Danish diabetes outpatient clinic
T Okdahl, AM Wegeberg, F Pociot, B Brock, J Størling… - BMJ open, 2022 - bmjopen.bmj.com
Objectives To investigate low-grade inflammation in type 2 diabetes and explore
associations to clinical aspects as well as microvascular and macrovascular complications …
associations to clinical aspects as well as microvascular and macrovascular complications …