Everything OLD is new again: How structural, functional, and bioinformatic advances have redefined a neglected nuclease family

EW Dot, LC Thomason, JS Chappie - Molecular Microbiology, 2023 - Wiley Online Library
Overcoming lysogenization defect (OLD) proteins are a conserved family of ATP‐powered
nucleases that function in anti‐phage defense. Recent bioinformatic, genetic, and …

Mechanism of RecF–RecO–RecR cooperation in bacterial homologous recombination

S Nirwal, M Czarnocki-Cieciura, A Chaudhary… - Nature Structural & …, 2023 - nature.com
In bacteria, one type of homologous-recombination-based DNA-repair pathway involves
RecFOR proteins that bind at the junction between single-stranded (ss) and double …

Elucidating recombination mediator function using biophysical tools

C Henry, SS Henrikus - Biology, 2021 - mdpi.com
Simple Summary This review recapitulates the initial knowledge acquired with genetics and
biochemical experiments on Recombination mediator proteins in different domains of life …

ComFC mediates transport and handling of single-stranded DNA during natural transformation

PP Damke, L Celma, SM Kondekar… - Nature …, 2022 - nature.com
The ComFC protein is essential for natural transformation, a process that plays a major role
in the spread of antibiotic resistance genes and virulence factors across bacteria. However …

Allosteric effects of SSB C-terminal tail on assembly of E. coli RecOR proteins

MK Shinn, AG Kozlov, TM Lohman - Nucleic acids research, 2021 - academic.oup.com
Escherichia coli RecO is a recombination mediator protein that functions in the RecF
pathway of homologous recombination, in concert with RecR, and interacts with E. coli …

Structural and Biochemical Analysis of the Recombination Mediator Protein RecR from Campylobacter jejuni

S Lee, SY Ahn, HB Oh, SY Kim, WS Song… - International Journal of …, 2023 - mdpi.com
The recombination mediator complex RecFOR, consisting of the RecF, RecO, and RecR
proteins, is needed to initiate homologous recombination in bacteria by positioning the …

Rec (F/O/R) proteins of the nitrogen-fixing cyanobacterium Nostoc PCC7120: In silico and expression analysis

S Pandey, A Kumar, A Kirti, GD Gupta, H Rajaram - Gene, 2021 - Elsevier
The high radioresistance of Nostoc sp. strain PCC7120 is indicative of a robust DNA repair
pathway. In the absence of NHEJ pathway and the canonical RecBCD proteins, the RecF …

ComF is a key mediator in single-stranded DNA transport and handling during natural transformation

PP Damke, L Celma, S Kondekar, AMD Guilmi… - bioRxiv, 2021 - biorxiv.org
Natural transformation plays a major role in the spreading of antibiotic resistances and
virulence factors. Whilst bacterial species display specificities in the molecular machineries …

[图书][B] Light and Life; Light-Dependent DNA Processes in Marine Cyanobacteria

AM Haney - 2020 - search.proquest.com
Marine Synechococcus are a group of globally widespread and ecologically significant
cyanobacteria that live in widely varying light conditions of oceanic waters. Cyanobacteria …

Pseudomonas aeruginosa​ genetics and virulence in cystic fibrosis and bacteraemia

S Kidman - 2020 - repository.cam.ac.uk
Pseudomonas aeruginosa​ is an opportunistic pathogen that can invade and colonise the
lungs of people with cystic fibrosis (CF), cause septic shock through bacteraemia infections …