There is currently an unmet need for effective treatment of chronic kidney disease (CKD) that
slows disease progression, prevents development of end-stage kidney disease and …

The endothelium is considered to be the gatekeeper of the vessel wall, maintaining and
regulating vascular integrity. In patients with chronic kidney disease, protective endothelial …

Insights from epidemiological, clinical and basic research are illuminating the interplay
between metabolic disorders, cardiovascular disease (CVD) and kidney dysfunction, termed …

Patients with chronic kidney disease (CKD) are at a highly increased risk of cardiovascular
complications, with increased vascular inflammation, accelerated atherogenesis and …

Atherosclerosis is one of the most fatal diseases in the world. The associated thickening of
the arterial wall and its background and consequences make it a very composite disease …

Arterial and venous thrombosis constitute a major source of morbidity and mortality
worldwide. Association between thrombotic complications and cardiovascular and other …

Glycosaminoglycans (GAGs) are a heterogeneous family of linear polysaccharides which
are composed of a repeating disaccharide unit. They are also linked to core proteins to form …

Recent evidence suggests that probiotics, prebiotics and synbiotics may serve as important
dietary components in the prevention (especially) and treatment of cardiovascular diseases …

Patients with chronic kidney disease (CKD) are at a high risk for cardiovascular disease
(CVD), and approximately half of all deaths among patients with CKD are a direct result of …

The medial layer of the arterial wall is composed mainly of vascular smooth muscle cells
(VSMCs). Under physiological conditions, VSMCs assume a contractile phenotype, and their …