Bronchiectasis refers to abnormal dilatation of the bronchi. Airway dilatation can lead to
failure of mucus clearance and increased risk of infection. Pathophysiological mechanisms …

Background Bronchiectasis is a heterogeneous, neglected disease with few multicentre
studies exploring the causes, severity, microbiology, and treatment of the disease across …

Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent
exacerbations in many patients. There have been no previous international guidelines. The …

Background Bronchiectasis is a common but neglected chronic lung disease. Most
epidemiological data are limited to cohorts from Europe and the USA, with few data from low …

Abstract 16S rRNA gene profiling, which contains nine hypervariable regions (V1–V9), is the
gold standard for identifying taxonomic units by high-throughput sequencing. Microbiome …

Chronic lung diseases are the third leading cause of death worldwide and are increasing in
prevalence over time. Although much of our traditional understanding of health and disease …

Summary European Respiratory Society guidelines for the management of adult
bronchiectasis highlight the paucity of treatment options available for patients with this …

Background International guidelines recommend airway clearance management as one of
the important pillars of bronchiectasis treatment. However, the extent to which airway …

Introduction Bronchiectasis is a multidimensional disease associated with substantial
morbidity and mortality. Two disease-specific clinical prediction tools have been developed …

Rationale: COPD and bronchiectasis are commonly reported together. Studies report
varying impacts of co-diagnosis on outcomes, which may be related to different definitions of …