Colon cancer is the third most predominant cancer caused by genetic, environmental and
nutritional factors. Plant-based compounds are very well known to regress colon cancer in …

Cancer is a severe health problem that continues to be a leading cause of death worldwide.
Increasing knowledge of the molecular mechanisms underlying cancer progression has led …

Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

Overwhelming evidence points to an abnormally active Wnt/β-catenin signaling as a key
player in colorectal cancer (CRC) pathogenesis. Ursolic acid (UA) is a pentacyclic …

The side-effects and long-term sequelae of anti-cancer chemotherapy remain a major
source of concern for both patients and clinicians despite the improved efficacy and …

Ursolic acid (UA) is a natural terpene compound exhibiting many pharmaceutical properties.
In this review the current state of knowledge about the health-promoting properties of this …

Although 5-fluorouracil (5-FU)-based chemotherapy is the major treatment for colorectal
cancer, it has disadvantages such as systemic toxicity, lack of effectiveness and selectivity …

The NF-κB family of transcription factors has an essential role in inflammation and innate
immunity. Furthermore, NF-κB is increasingly recognized as a crucial player in many steps of …

Despite significant advancements made in the treatment of cancer during the past several
decades, it remains one of the leading causes of death worldwide killing approximately 9.6 …

Colorectal cancer (CRC) is the third most common diagnosed malignancy among both
sexes in the United States as well as in the European Union. While the incidence and …