Objective Care for fear of cancer recurrence (FCR) is considered the most common unmet
need among cancer survivors. Yet the prevalence of FCR and predisposing factors remain …

Objective To characterise the determinants, time course, and risks of acute myocardial
infarction associated with use of oral non-steroidal anti-inflammatory drugs (NSAIDs) …

Prediction models in health care use predictors to estimate for an individual the probability
that a condition or disease is already present (diagnostic model) or will occur in the future …

Because missing data are present in almost every study, it is important to handle missing
data properly. First of all, the missing data mechanism should be considered. Missing data …

Background Current strategies for preventing severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection are limited to nonpharmacologic interventions …

Importance Maternal hypothyroidism and hyperthyroidism are risk factors for preterm birth.
Milder thyroid function test abnormalities and thyroid autoimmunity are more prevalent, but it …

Meta‐analysis using individual participant data (IPD) obtains and synthesises the raw,
participant‐level data from a set of relevant studies. The IPD approach is becoming an …

Access to big datasets from e-health records and individual participant data (IPD) meta-
analysis is signalling a new advent of external validation studies for clinical prediction …

Missing data pose challenges to real-life data analysis. Simple ad-hoc fixes, like deletion or
mean imputation, only work under highly restrictive conditions, which are often not met in …

Background Selection of candidates for lung cancer screening based on individual risk has
been proposed as an alternative to criteria based on age and cumulative smoking exposure …