The changing therapeutic landscape of head and neck cancer
Head and neck cancers are a heterogeneous collection of malignancies of the upper
aerodigestive tract, salivary glands and thyroid. In this Review, we primarily focus on the …
aerodigestive tract, salivary glands and thyroid. In this Review, we primarily focus on the …
Targeted therapy for head and neck cancer: signaling pathways and clinical studies
Head and neck cancer (HNC) is malignant, genetically complex and difficult to treat and is
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
the sixth most frequent cancer, with tobacco, alcohol and human papillomavirus being major …
Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non …
Background Patients with human papillomavirus (HPV)-positive oropharyngeal squamous
cell carcinoma have high survival when treated with radiotherapy plus cisplatin. Whether …
cell carcinoma have high survival when treated with radiotherapy plus cisplatin. Whether …
Cetuximab, docetaxel, and cisplatin versus platinum, fluorouracil, and cetuximab as first-line treatment in patients with recurrent or metastatic head and neck …
J Guigay, A Aupérin, J Fayette, E Saada-Bouzid… - The Lancet …, 2021 - thelancet.com
Background Results from a phase 2 trial of the TPEx chemotherapy regimen (docetaxel–
platinum–cetuximab) showed promising results, with a median overall survival of 14· 0 …
platinum–cetuximab) showed promising results, with a median overall survival of 14· 0 …
Guidelines of care for the management of cutaneous squamous cell carcinoma
M Alam, A Armstrong, C Baum, JS Bordeaux… - Journal of the American …, 2018 - Elsevier
Cutaneous squamous cell carcinoma (cSCC) is the second most common form of human
cancer and has an increasing annual incidence. Although most cSCC is cured with office …
cancer and has an increasing annual incidence. Although most cSCC is cured with office …
Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas
Purpose: The genetic differences between human papilloma virus (HPV)–positive and–
negative head and neck squamous cell carcinomas (HNSCC) remain largely unknown. To …
negative head and neck squamous cell carcinomas (HNSCC) remain largely unknown. To …
[HTML][HTML] Therapeutic approaches for the treatment of head and neck squamous cell carcinoma–An update on clinical trials
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common non-skin
cancer with a tobacco consumption and infection with high-risk human papillomavirus (HPV) …
cancer with a tobacco consumption and infection with high-risk human papillomavirus (HPV) …
Human papillomavirus and overall survival after progression of oropharyngeal squamous cell carcinoma
C Fakhry, Q Zhang, PF Nguyen-Tan… - Journal of clinical …, 2014 - ascopubs.org
Purpose Risk of cancer progression is reduced for patients with human papillomavirus
(HPV)–positive oropharynx cancer (OPC) relative to HPV-negative OPC, but it is unknown …
(HPV)–positive oropharynx cancer (OPC) relative to HPV-negative OPC, but it is unknown …
Current treatment options for recurrent or metastatic head and neck squamous cell carcinoma
AG Sacco, EE Cohen - Journal of clinical oncology, 2015 - ascopubs.org
This review highlights the evidence-based data to support current best management
practices for patients with recurrent and/or metastatic (R/M) head and neck squamous cell …
practices for patients with recurrent and/or metastatic (R/M) head and neck squamous cell …
[HTML][HTML] The emerging role of immunotherapy in head and neck squamous cell carcinoma (HNSCC): anti-tumor immunity and clinical applications
P Economopoulou, C Perisanidis… - Annals of …, 2016 - ncbi.nlm.nih.gov
Head and neck squamous cell carcinoma (HNSCC) carries a poor prognosis, with low
survival rates for advanced stage tumors and minimal improvement in survival trends …
survival rates for advanced stage tumors and minimal improvement in survival trends …