The free radical oxidants such as reactive oxygen species, reactive nitrogen species, and
reactive sulfur species are produced inside cells through various metabolic processes. The …

Free radicals are found to be involved in both initiation and promotion of multistage
carcinogenesis. These highly reactive compounds can act as initiators and/or promoters …

Reactive oxygen species (ROS) play an important role in determining the fate of normal
stem cells. Low levels of ROS are required for stem cells to maintain quiescence and self …

Diminished amounts of manganese-containing superoxide dismutase have been found in
all the tumors examined to date. Lowered amounts of the copper-zinc-containing superoxide …

A simple and reproducible microtiter plate assay for measuring superoxide dismutase (SOD)
activity is described. Water-soluble tetrazolium, the sodium salt of 4-[3-(4iodophenyl)-2-(4 …

OBJECTIVES: To observe the changes in the antioxidative defense enzymes and to detect
the alterations of renal microscopy after carbon tetrachloride (CCl4) administration in rats …

Living creatures find, in molecular oxygen, both benefit and detriment. Thus, while being
useful to aerobes as an electron sink for energy-yielding reactions and as a reagent for …

Copper‐and zinc‐containing superoxide dismutase (Cu‐ZnSOD), manganese‐containing
superoxide dismutase (MnSOD), catalase (CAT), glutathione peroxidase (GPX, both Se …

Publisher Summary This chapter focuses on the role that selenium (Se) compounds play in
the inhibition or slowing of the induction of cancer by chemicals and other agents. Se has …

Several studies point to the existence of a disturbance in the metabolism of the reactive
species of oxygen in cancer cells. Based on this evidence, and in particular on a …