SUMMARY ANSWER: Pregnant women with hereditary thrombophilia have an increased
risk of RPL, especially for pregnant women with the G1691A mutation of the factor V Leiden …

Human reproduction is extraordinarily wasteful. The reasons for this have taxed all of the
contributors to this book. As we move into the 21st century it is sobering to reflect on the fact …

The few days before and after birth are a time of special risk for stroke in both mother and
infant, probably related to activation of coagulation mechanisms in this critical period …

Recurrent spontaneous abortion (RSA) is defined as three or more consecutive pregnancy
losses prior to the 20th week of gestation. The etiology of recurrent spontaneous abortion is …

Background Recurrent pregnancy loss (RPL) is a significant clinical problem. Recently,
thrombophilias have been implicated as a possible cause. Factor V Leiden (FVL) and …

Pregnancy is hypercoagulable state. The field of thrombophilia; the tendency to thrombosis,
has been developed rapidly and has been linked to many aspects of pregnancy. It is …

OBJECTIVE: This systematic review examines the strength of the association between
thrombophilia and recurrent pregnancy loss and other serious obstetric complications …

Activated protein C (APC) resistance, both in its congenital form, due to the factor V Leiden
mutation, and in its acquired form, are important risk factors for systemic venous thrombosis …

Problem Recurrent miscarriage is a heterogeneous condition. While the role of acquired
thrombophilia has been accepted as an etiology of recurrent miscarriage, the contribution of …

PROBLEM: Placental perfusion may be compromised by increased thrombosis that leads to
pregnancy complications and recurrent pregnancy loss (RPL). Since heritable thrombophilic …