Elastic fibers are essential constituents of the extracellular matrix of higher vertebrates and
endow several tissues and organs including lungs, skin and blood vessels with elasticity …

with the matrix and with the periodicity of negative charges on collagen. Crystals initially
form octacalcium phosphate [Ca8H2 (PO4) 6· 5H2O], which reorganizes and seeds epitaxial …

Background Respiratory failure and thromboembolism are frequent in severe acute
respiratory syndrome coronavirus 2–infected patients. Vitamin K activates both hepatic …

Cardiovascular complications are the leading cause of death in patients with chronic kidney
disease (CKD). Vascular calcification is a common complication in CKD, and investigators …

Coronavirus disease 2019 (Covid-19), caused by severe acute respiratory syndrome
coronavirus (SARS-CoV)-2, exerts far-reaching effects on public health and socio-economic …

Vascular calcification or ectopic mineralization in blood vessels is an active, cell-regulated
process, increasingly recognized as a general cardiovascular risk factor. Remarkably …

Calcification of vessels reduces their elasticity, affecting hemodynamic parameters of the
cardiovascular system. The development of arterial hypertension, cardiac hypertrophy …

Written by more than 400 subject experts representing diverse academic and applied
domains, this multidisciplinary resource surveys the vanguard of biomaterials and …

Ductal carcinoma in situ (DCIS)—a significant precursor to invasive breast cancer—is
typically diagnosed as microcalcifications in mammograms. However, the effective use of …

Degradation of elastin, the main amorphous component of elastic fibers, by elastases
belonging to the serine, metallo, or cysteine families leads to the generation of elastin …