Can we suppress chronic systemic inflammation and postpone age-related diseases by targeting the IgG glycome?

G Lauc - Expert Opinion on Therapeutic Targets, 2023 - Taylor & Francis
Introduction Glycans attached to immunoglobulin G are an important regulator of chronic
systemic inflammation, one of the key drivers of aging. As people age, glycans that suppress …

Long-Term Culturing of FreeStyle 293-F Cells Affects Immunoglobulin G Glycome Composition

F Lukšić, A Mijakovac, G Josipović, V Vičić Bočkor… - Biomolecules, 2023 - mdpi.com
Glycosylation of IgG regulates the effector function of this antibody in the immune response.
Glycosylated IgG is a potent therapeutic used for both research and clinical purposes. While …