The incidence of kidney diseases is increasing globally, posing a serious threat to human
health. Studies have shown that apigenin, a natural dietary flavonoid with multiple …

Background Primary tumor removal by cytoreductive nephrectomy in synchronous
metastatic renal cell carcinoma patients has been investigated in the context of various …

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer
characterized by metabolic reprogramming. Glutamine metabolism is pivotal in metabolic …

Background Management of localized renal cell carcinoma (RCC) is challenged by
inaccurate methods to assess the risk of recurrence and deferred detection of relapse and …

Objective A novel systemic immune-inflammation index (SII), based on the neutrophils,
lymphocytes, and platelet counts, is associated with the prognosis of several cancers …

Identification of effective adjuvant therapies for renal cell carcinoma remains challenging
despite the development of immune checkpoint inhibitors. Enhancement of the design of …