Aortic stenosis (AS) is a dynamic degenerative process that shares many pathophysiological
features with atherogenesis, from initial proinflammatory calcification and focal thickening of …

Aims Degenerative aortic valve stenosis with preserved ejection fraction (ASpEF) and heart
failure with preserved ejection fraction (HFpEF) display intriguing similarities. This study …

Epicardial adipose tissue (EAT) has the unique property to release mediators that nourish
the heart in healthy conditions, an effect that becomes detrimental when volume expands …

Importance Increased ability to quantify anatomical phenotypes across multiple organs
provides the opportunity to assess their cumulative ability to identify individuals at greatest …

Background Epicardial adipose tissue (EAT) is involved in inflammation and associated with
cardiovascular risk factors. It is not known whether EAT affects outcome of patients …

Aims Genetic and environmental factors all interact in the risk of progression of valvular
dysfunctions. Previous studies reported a relation between valve diseases and epicardial …

Background Inflammation is involved in the progression of degenerative valvular heart
disease (DVHD). microRNA-222 (miR-222) contributes to inflammation-mediated vascular …

Introduction Epicardial fat is a variety of visceral adipose tissue that secretes pro-
inflammatory cytokines that can lead to progression of atherosclerosis. Previous studies …

Background Epicardial fat is a true visceral fat deposit with adverse effects through the
secretion of numerous proinflammatory and proatherogenic cytokines. Previous studies …

Background: Mitral annular calcification (MAC) is associated with several cardiovascular
disorders including coronary artery disease (CAD), atrial fibrillation, heart failure, ischemic …