The future of rodent models in depression research
Currently, over 300 million people worldwide have depression, and the socioeconomic
burden of this debilitating disorder is anticipated to increase markedly over the coming …
burden of this debilitating disorder is anticipated to increase markedly over the coming …
Ethological approach to social isolation effects in behavioral studies of laboratory rodents
H Arakawa - Behavioural brain research, 2018 - Elsevier
The aim of the present review is to discuss how housing conditions affect behavioral
performance in laboratory rodents from an ethological view. Commonly used laboratory …
performance in laboratory rodents from an ethological view. Commonly used laboratory …
[HTML][HTML] Molecular and neurocircuitry mechanisms of social avoidance
AK Gellner, J Voelter, U Schmidt, EC Beins… - Cellular and Molecular …, 2021 - Springer
Humans and animals live in social relationships shaped by actions of approach and
avoidance. Both are crucial for normal physical and mental development, survival, and well …
avoidance. Both are crucial for normal physical and mental development, survival, and well …
[HTML][HTML] The social instability stress paradigm in rat and mouse: A systematic review of protocols, limitations, and recommendations
A Koert, A Ploeger, CLH Bockting, MV Schmidt… - Neurobiology of …, 2021 - Elsevier
Background Social stress is an important environmental risk factor for the development of
psychiatric disorders, including depression and anxiety disorders. Social stress paradigms …
psychiatric disorders, including depression and anxiety disorders. Social stress paradigms …
[HTML][HTML] Psychological stress, its reduction, and long-term consequences: What studies with laboratory animals might teach us about life in the dog shelter
MB Hennessy, RM Willen, PA Schiml - Animals, 2020 - mdpi.com
Simple Summary Experiments in laboratory animals have provided the basis for studies of
stress, its reduction, and its long-term consequences in shelter dogs. Stressors often used in …
stress, its reduction, and its long-term consequences in shelter dogs. Stressors often used in …
[HTML][HTML] Targeting oxytocin receptor (Oxtr)-expressing neurons in the lateral septum to restore social novelty in autism spectrum disorder mouse models
M Horiai, A Otsuka, S Hidema, Y Hiraoka, R Hayashi… - Scientific reports, 2020 - nature.com
Autism spectrum disorder (ASD) is a continuum of neurodevelopmental disorders and needs
new therapeutic approaches. Recently, oxytocin (OXT) showed potential as the first anti …
new therapeutic approaches. Recently, oxytocin (OXT) showed potential as the first anti …
Social status in mouse social hierarchies is associated with variation in oxytocin and vasopressin 1a receptor densities
The neuropeptides oxytocin and vasopressin and their receptors have established roles in
the regulation of mammalian social behavior including parental care, sex, affiliation and pair …
the regulation of mammalian social behavior including parental care, sex, affiliation and pair …
[HTML][HTML] Long-term impacts of post-weaning social isolation on nucleus accumbens function
CJ Bendersky, AA Milian, MD Andrus… - Frontiers in …, 2021 - frontiersin.org
Adolescence is a period of incredible change, especially within the brain's reward circuitry.
Stress, including social isolation, during this time has profound effects on behaviors …
Stress, including social isolation, during this time has profound effects on behaviors …
Social network stability is impacted by removing a dominant male in replicate dominance hierarchies of a cichlid fish
TJ Piefke, TR Bonnell, GM DeOliveira, SE Border… - Animal Behaviour, 2021 - Elsevier
Highlights•Cichlid fish form dominance hierarchies in which males fight for territories.•In
groups of cichlid fish, we vacated a territory by removing a territorial male.•This created …
groups of cichlid fish, we vacated a territory by removing a territorial male.•This created …
Long-lasting effects of postweaning sleep deprivation on cognitive function and social behaviors in adult mice
B Huang, B Sun, R Yang, S Liang, X Li, Y Guo… - …, 2022 - Elsevier
Sleep deprivation (SD) has adverse effects on physical and mental health. Recently
increasing attention has been given to SD in the early-life stage. However, the effects and …
increasing attention has been given to SD in the early-life stage. However, the effects and …