Environmental cycles, melatonin, and circadian control of stress response in fish

FJ Sánchez-Vázquez, JF López-Olmeda… - Frontiers in …, 2019 - frontiersin.org
Fish have evolved a biological clock to cope with environmental cycles, so they display
circadian rhythms in most physiological functions including stress response. Photoperiodic …

Peripheral and central effects of melatonin on blood pressure regulation

O Pechanova, L Paulis, F Simko - International journal of molecular …, 2014 - mdpi.com
The pineal hormone, melatonin (N-acetyl-5-methoxytryptamine), shows potent receptor-
dependent and-independent actions, which participate in blood pressure regulation. The …

[HTML][HTML] The morphological and functional characteristics of the pineal gland

BA Gheban, IA Rosca, M Crisan - Medicine and pharmacy reports, 2019 - ncbi.nlm.nih.gov
Results We have reviewed physiological information of melatonin and DMT, anatomical,
histological and histopathological information on the pineal gland and its role in endocrine …

Elevated heart rate and nondipping heart rate as potential targets for melatonin: a review

F Simko, T Baka, L Paulis… - Journal of pineal …, 2016 - Wiley Online Library
Elevated heart rate is a risk factor for cardiovascular and all‐cause mortalities in the general
population and various cardiovascular pathologies. Insufficient heart rate decline during the …

Agomelatine, venlafaxine, and running exercise effectively prevent anxiety-and depression-like behaviors and memory impairment in restraint stressed rats

S Lapmanee, J Charoenphandhu, J Teerapornpuntakit… - PloS one, 2017 - journals.plos.org
Several severe stressful situations, eg, natural disaster, infectious disease out break, and
mass casualty, are known to cause anxiety, depression and cognitive impairment, and …

Gestational chronodisruption impairs circadian physiology in rat male offspring, increasing the risk of chronic disease

N Mendez, D Halabi, C Spichiger, ER Salazar… - …, 2016 - academic.oup.com
Chronic exposure to light at night, as in shift work, alters biological clocks (chronodisruption),
negatively impacting pregnancy outcome in humans. Actually the interaction of maternal and …

Melatonin-mediated FKBP4 downregulation protects against stress-induced neuronal mitochondria dysfunctions by blocking nuclear translocation of GR

MJ Kim, GE Choi, CW Chae, JR Lim, YH Jung… - Cell Death & …, 2023 - nature.com
The physiological crosstalk between glucocorticoid and melatonin maintains neuronal
homeostasis in regulating circadian rhythms. However, the stress-inducing level of …

Melatonin as an anti-stress signal: effects on an acute stress model and direct actions on interrenal tissue in goldfish

C Azpeleta, MJ Delgado, JR Metz, G Flik… - Frontiers in …, 2024 - frontiersin.org
Background Melatonin is a key hormone in regulation of circadian rhythms, and involved in
many rhythmic functions, such as feeding and locomotor activity. Melatonin reportedly …

Melatonin levels in children with obesity are associated with metabolic risk and inflammatory parameters

M Gombert, V Martin-Carbonell, G Pin-Arboledas… - Nutrients, 2021 - mdpi.com
Melatonin, the hormone of circadian rhythm regulation, is involved in the modulation of
mitochondrial activity through its antioxidant and anti-inflammatory properties. Alteration of …

[HTML][HTML] Neuroprotective effects of melatonin administration against chronic immobilization stress in rats

AMS Gomaa, HM Galal… - International journal of …, 2017 - ncbi.nlm.nih.gov
Chronic stress can impair brain functions and play a well-known role in the development of
stress-related disorders such as anxiety. Melatonin (Mel) is a neurohormone which regulate …